产品详情
英文名称 DRAM
中文名称 DNA损伤自噬调整蛋白抗体
别 名 Damage regulated autophagy modulator; Damage-regulated autophagy modulator; DNA damage-regulated autophagy modulator protein 1; dram1; DRAM1_HUMAN.
说 明 书 0.1ml 0.2ml
研究领域 肿瘤 心血管 免疫学 细胞凋亡
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Sheep,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 DNA损伤自噬调整蛋白抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 26kDa
细胞定位 细胞浆 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DRAM
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DNA损伤自噬调整蛋白抗体产品介绍 background:
This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008]
Function:
Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy.
Subcellular Location:
Lysosome membrane; Multi-pass membrane protein.
Similarity:
Belongs to the DRAM/TMEM150 family.
Gene ID:
55332
Database links:
Entrez Gene: 55332 Human
Entrez Gene: 71712 Mouse
Omim: 610776 Human
SwissProt: Q8N682 Human
SwissProt: Q9DC58 Mouse
Unigene: 525634 Human
Unigene: 35450 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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hz-9082R AKIRIN2 AKIRIN2蛋白抗体
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hz-9084R FBXW12/FBXO35 FBXW12蛋白抗体
hz-9085R FBXO42 FBXO42蛋白抗体
hz-9087R FBXO4 FBXO4蛋白抗体
hz-9088R FBXO28 FBXO28蛋白抗体
hz-9089R FBXO27 FBXO27蛋白抗体
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hz-9094R AHNAK2 AHNAK核蛋白2抗体
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hz-9096R AER61 未知糖基化转移酶AER61抗体
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hz-9100R ARSF 芳香基硫酸酯酶F抗体
hz-9101R ARSH 芳香基硫酸酯酶H抗体
hz-9102R ARSK 芳香基硫酸酯酶K抗体
hz-9103R ART3 二磷酸腺苷核糖基转移酶3抗体
hz-9104R Tankyrase 端粒调控因子抗体
hz-9105R ART5 二磷酸腺苷核糖基转移酶5抗体
hz-9106R ASB13 含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族13抗体
hz-9107R ASC2/POP1 感染性蛋白唯一蛋白1抗体
hz-9108R ATAD3A/B/C 三磷酸腺苷酶家族蛋白3A抗体
hz-9109R MAP4K6/MINK1 丝裂原活化蛋白激酶MAP4K6抗体
hz-9110R ATAD2 三磷酸腺苷酶家族蛋白2抗体
hz-9112R ASMTL ASMTL蛋白抗体
hz-9113R GPCR TAS1R3 G蛋白偶联受体TAS1R3抗体
hz-9114R BAGE2 肿瘤/睾丸抗原2.2抗体
hz-9115R BAGE3 肿瘤/睾丸抗原2.3抗体