产品详情
shank-1抗体
产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
shank-1抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
shank-1抗体
产品介绍
TGN Marker
有学者认为:shank-1似乎是具有兴奋性突触PSD中的连接蛋白,它可以连接后突触膜受体,包括NMDA-Type和谷氨酸受体等。在树突旋转和突触连接的有机体功能和结构方面起重要作用。shank1 主要表达在脑组织内,属于shank家族。
The mechanisms underlying the molecular assemblage of molecules at the synapse are not well understood. Recently, a number of novel anchoring/scaffold proteins that are associated with postsynaptic density (PSD) proteins have been isolated. SHANK1, SHANK2 and SHANK3 constitute a family of proteins that may function as molecular scaffolds in the PSD. SHANK is made of five domain/regions that are probably involved in protein-protein interactions: ankyrin repeats, an SH3 domain, a PDZ domain, a SAM domain, and a proline rich region. SHANK interacts directly with GKAP or SAPAP via its PDZ domain, thus potentially bridging the N-methyl-D-aspartate receptor (NMDA)-PSD-95-GKAP complex.
237kDa
Other Aliases:
GKAP/SAPAP interacting protein; SH3 and multiple ankyrin repeat domains 1; SH3 and multiple ankyrin repeat domains protein 1; SHANK 1; Somatostatin receptor interacting protein; Somatostatin receptor-interacting protein; SPANK 1; SPANK1; SSTR interacting protein; SSTRIP; Synamon
xy-13900R CHIA哺乳动物酸性几丁质酶抗体
shank-1抗体
xy-13902R CHID1几丁质酶结构域蛋白1抗体
xy-13903R Chimaerin 2嵌合蛋白2/β2-chimaerin抗体
xy-13904R CHIT1几丁质酶1抗体
xy-10093R CD97 antigen subunit alpha白细胞抗原CD97 alpha 抗体
xy-7125R Claudin 2紧密连接蛋白2抗体
xy-8482R Claudin 7紧密连接蛋白7抗体
xy-15152R C2orf53 2号染色体开放阅读框53抗体
xy-15153R C2orf542号染色体开放阅读框54抗体
xy-15154R C2orf562号染色体开放阅读框56抗体
xy-15155R C2orf612号染色体开放阅读框61抗体
xy-4763R CA153乳腺癌相关抗原抗体
xy-5113R CDCA4细胞分裂周期相关蛋白4抗体
xy-5115R Cytochrome b5细胞色素b5抗体
xy-2377R CNR2钙粘蛋白相关的神经受体2抗体
xy-15046R C1orf1861号染色体开放阅读框186抗体
xy-8871R CXCL16CXC趋化因子16抗体
xy-4878R Complement C3c alpha' chain fragment 2补体C3cα片段2抗体
xy-4874R Complement C3c alpha' chain fragment 1补体C3cα 链片段1抗体
xy-4875R Complement C3dg fragment补体C3dg片段抗体
xy-4876R Complement C3g fragment补体C3g片段抗体
xy-4877R Complement C3d fragment补体C3d片段抗体
xy-8865R CD28CD28抗体
xy-5128R CAPZA2F肌动蛋白α2亚基抗体
xy-5135R CREM环磷酸腺苷反应元件调节蛋白抗体
xy-5114R Cystatin A胱抑素A/半胱氨酸蛋白酶抑制剂A抗体
xy-5112R CLIC1氯离子通道蛋白27抗体
xy-5016R Claudin 8紧密连接蛋白8抗体
xy-5241R Phospho-Caspase-9 (Ser196)磷酸化半胱氨酸蛋白酶9抗体
xy-5245R phospho-Cdc25B (Ser353)磷酸化细胞分裂周期蛋白25B抗体
xy-5228R phospho-CDKN1B (Thr157)磷酸化P27抗体/周期素依赖激酶抑制剂抗体
xy-5229R phospho-CDKN1B (Thr187)磷酸化P27抗体/周期素依赖激酶抑制剂抗体
xy-5236R phospho-CDKN1B (Ser178)磷酸化P27抗体/周期素依赖激酶抑制剂抗体
xy-5237R phospho-CDKN1A (Thr145)磷酸化p21蛋白抗体
xy-5238R phospho-CDKN1A (Thr57)磷酸化p21蛋白抗体
xy-15304R c8orf848号染色体开放阅读框84抗体
xy-5239R phospho-CDKN1A (Ser146)磷酸化p21蛋白抗体