英文名称    Etv5    

中文名称    转录因子Ets差异基因5抗体    

别    名    ERM; Ets related protein ERM; ETS translocation variant 5; Ets variant gene 5; Ets-related protein ERM; Etv5; ETV5_HUMAN.    

说 明 书    0.2ml      

研究领域    肿瘤  干细胞  转录调节因子  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 转录因子Ets差异基因5抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    58kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human ERM/Etv5 (301-385aa)    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

转录因子Ets差异基因5抗体产品介绍    background:

Rad and Gem related GTP binding protein (REM) is a member of the RGK subfamily of Ras-like GTPases that also includes Rad, REM2 and Gem/Kir. REM is a phosphorylated protein that is highly expressed in cardiac muscle and moderately expressed in lung, kidney and skeletal muscle. REM associates with several 14-3-3 isoforms as well as with calmodulin in a calcium-dependent manner. REM mediates two distinct signal transduction pathways that regulate both cytoskeletal reorganization and voltage-gated calcium channel activity. REM decreases the current that passes through cardiac voltage-gated L-type Ca channels (Ca(V)). Overexpression of REM may result in the development of cytoplasmic processes, reorganization of the Actin cytoskeleton, reduction in focal adhesion size and an elongated or dendritic-like cell morphology.

Function:
Binds to DNA sequences containing the consensus nucleotide core sequence GGAA.

Subcellular Location:
Ubiquitous.

Tissue Specificity:
Nucleus.

Similarity:
Belongs to the ETS family.
Contains 1 ETS DNA-binding domain.

Database links:
UniProtKB/Swiss-Prot: P41161.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

转录因子Ets差异基因5抗体

hz-4060R phospho-MYL9(Thr19)  磷酸化肌球蛋白轻链9抗体

hz-3658R NIPP1/ARD1  核抑制蛋白磷酸酶1抗体

hz-0337R Myelin Protein Zero  外周髓磷脂P0蛋白/P0蛋白抗体

hz-2032R PMP2  周围神经髓鞘蛋白2抗体

hz-2166R MYSM1  MYSM1抗体

hz-1267R MYOZ/MYOZ1  MYOZ抗体

hz-2442R MyoD1/Myf3  肌原调节蛋白抗体

hz-5499R phospho-MyoD1(Ser200)  磷酸化肌原调节蛋白抗体

hzt-0509M SM Myosin (Smooth Muscle)  人心肌肌凝蛋白(平滑肌) 小鼠单抗

hz-3805R Myoglobin  肌红蛋白抗体

hz-1038R CHRNA4  烟碱型乙酰胆碱受体α4抗体

hz-1049R CHRNA7  烟碱型乙酰胆碱受体α7抗体

hz-2538R CHRNA2(neuronal)  烟碱型乙酰胆碱受体A2(神经型)抗体

hz-4247R CHRNB2  烟碱型乙酰胆碱受体B2抗体

hz-3682R Nox1/NADPH oxidase 1  有丝分裂氧化酶1抗体

hz-3683R Nox3/NADPH oxidase 3  NADPH oxidase 3抗体

hz-3684R NOX4/NADPH oxidase 4  NADPH氧化酶NOX家族的成员4抗体

hz-0829R Nanog  胚胎干细胞关键蛋白抗体

hz-0452R NAIF1 protein  核凋亡诱导因子蛋白1

hz-0903R Natrexone  纳曲酮抗体IgG

hz-1052R NAP1L1  核小体组装蛋白1抗体

hz-1797R Contactin 6/NB3/CNTN6  神经细胞NB3特定蛋白抗体

hz-2667R Contactin-1  神经细胞表面蛋白F3

hz-1995R P95/NBS1  DNA修复蛋白NBS1抗体

hz-3718R Phospho-p95/NBS1 (Ser343)  磷酸化DNA修复蛋白NBS1抗体

hz-6579R GH/Growth Hormone  生长激素抗体

hz-1172R CDH2/N-cadherin  N-钙粘附分子抗体

hz-5263R phospho-CDH2 (Tyr820)  磷酸化N-钙粘附分子抗体

hz-1519R E-cadherin/CD324  上皮钙粘附分子抗体

hz-5822R H Cadherin/CDH13  心脏钙粘蛋白抗体

hz-5823R K Cadherin  钙粘蛋白6抗体

hz-1466R Nck1/NCK alpha  NCK衔接蛋白1抗体

hz-4280R NCK2/Nck beta  NCK衔接蛋白2抗体

hz-5112R NCC27/CLIC1  氯离子通道蛋白27抗体