产品详情
英文名称 GPR183
中文名称 G蛋白偶联受体183抗体
别 名 ebi 2; EBI2; EBV induced G protein coupled receptor 2; EBV-induced G-protein coupled receptor 2; ebv-induced gene 2; Epstein-Barr virus-induced gene 2; Epstein Barr virus induced gene 2; epstein-barr virus induced gene 2; Epstein-Barr virus-induced G-protein coupled receptor 2; G protein-coupled receptor 183; G-protein coupled receptor 183; GP183_HUMAN; gpr183; Lymphocyte specific G protein coupled receptor.
说 明 书 0.1ml 0.2ml
研究领域 细胞生物 信号转导 细菌及病毒 G蛋白偶联受体 G蛋白信号 细胞膜蛋白
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 G蛋白偶联受体183抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human EBV Induced Gene 2
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
G蛋白偶联受体183抗体产品介绍 background:
Epstein-Barr virus-induced gene 2 is a 357 amino acid multi pass membrane protein. It is expressed in B-lymphocytes and lymphoid tissues and may function in the modulation of the immune system. Out of the nine genes that are induced by the Epstein-Barr virus, Ebi2 exhibits the highest levels of up-regulation. Ebi2 is a G-protein coupled receptor that signals through the G-protein G錳. Ebi2 contains seven hydrophobic transmembrane regions and a putative N-linked glycosylation site at its extracellular N-terminus. Ebi2 is believed to be involved in regulating the effects of the Epstein-Barr virus on B-lymphocytes. In addition, Ebi2 may play a role mediating normal lymphocyte functions.
Function:
Orphan receptor that plays a central role during humoral immunity. Promotes activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses (By similarity). Signals constitutively through G(i)-alpha, but not G(s)-alpha or G(q)-alpha.
Subcellular Location:
Cell membrane.
Tissue Specificity:
Expressed abundantly in lymphoid tissues such as spleen and lymph node, and in B- and T-lymphocytes. Also highly expressed in lung, heart and gastrointestinal tract, and weakly expressed in the urogenital system and brain.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
Gene ID:
1880
G蛋白偶联受体183抗体
hze-0292P BSA/HRP 辣根过氧化物酶标记牛血清白蛋白
hze-0361P rec Protein G/HRP 辣根过氧化物酶标记的重组蛋白G
hz-0855P-HRP Insulin/HRP 辣根过氧化物酶标记人胰岛素蛋白
hz-0311P-AP Biotin/AP 碱性磷酸酶标记生物素
hz-0312P-AP Avidin/AP 碱性磷酸酶标记亲合素
hz-0437P-AP Streptavidin/AP 碱性磷酸酶标记链霉亲和素
hz-0360G-AP Goat Anti-human IgA/AP 碱性磷酸酶标记羊抗人IgA
hz-0360R-AP Rabbit Anti-human IgA/AP 碱性磷酸酶标记兔抗人IgA
hz-0362P-AP Protein A/AP 碱性磷酸酶标记的蛋白A
hz-0292P-AP BSA/AP 碱性磷酸酶标记标记牛血清白蛋白
hz-0361P-AP rec Protein G/AP 碱性磷酸酶标记的重组蛋白G
hzb-0360G Goat Anti-human IgA/Biotin 生物素化羊抗人IgA
hza-0297R Rabbit Anti-human IgG/Streptavidin 链霉亲和素标记兔抗人IgG
hzb-0295P Rabbit IgG/Biotin 生物素化兔IgG
hzb-0297P human IgG/Biotin 生物素化人IgG
hzb-0296P mouse IgG/Biotin 生物素化小鼠IgG
hzF-0292P BSA/FITC 荧光素标记牛血清白蛋白
hzF-0366R Rb Anti-FITC/FITC 荧光素标记兔抗FITC
hzF-0360G Goat Anti-human IgA/FITC 荧光素标记羊抗人IgA
hzR-0292P BSA/RBITC 罗丹明标记牛血清白蛋白
hzR-0437P Streptavidin/RBITC 红色荧光素罗丹明标记链霉亲和素
hzR-0295P Rabbit IgG/RBITC 罗丹明标记兔IgG(细胞流式同型对照)
hzR-0296P Mouse IgG/RBITC 罗丹明标记小鼠IgG(细胞流式同型对照)
hzR-0294P Goat IgG/RBITC 罗丹明标记羊IgG(细胞流式同型对照)
hzR-0293P Rat IgG/RBITC 罗丹明标记大鼠IgG(细胞流式同型对照)
hzF-0312P Avidin/FITC 荧光素标记亲合素
hzF-0437P Streptavidin/FITC 荧光素标记链霉亲和素
hzF-0361P rec Protein G/FITC 荧光素标记重组纯化蛋白G
hzF-0362P Protein A/FITC FITC标记重组金黄色葡萄球菌蛋白A
hzR-0366R Rb Anti-FITC/RBITC 罗丹明标记兔抗FITC
hzR-0360G Goat Anti-human IgA/RBITC 罗丹明标记羊抗人IgA
hzR-0312P Avidin/RBITC 罗丹明标记亲合素
hzR-0362P Protein A/RBITC 罗丹明标记蛋白A
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