产品详情
英文名称 Encephalopsin
中文名称 感光视觉蛋白ECPN抗体
别 名 ECPN; Encephalopsin; ERO; NMO 1; NMO1; OPN 3; OPN3; OPN3_HUMAN; Opsin 3; Opsin-3; Opsin3; Panopsin.
说 明 书 0.1ml 0.2ml
研究领域 神经生物学 G蛋白偶联受体 G蛋白信号
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Horse, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 感光视觉蛋白ECPN抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Encephalopsin
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
感光视觉蛋白ECPN抗体产品介绍 background:
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein. [provided by RefSeq, Jul 2008]
Function:
May play a role in encephalic photoreception.
Subcellular Location:
Membrane.
Tissue Specificity:
Strongly expressed in brain. Highly expressed in the preoptic area and paraventricular nucleus of the hypothalamus. Shows highly patterned expression in other regions of the brain, being enriched in selected regions of the cerebral cortex, cerebellar Purkinje cells, a subset of striatal neurons, selected thalamic nuclei, and a subset of interneurons in the ventral horn of the spinal cord.
Similarity:
Belongs to the G-protein coupled receptor 1 family. Opsin subfam
Gene ID:
23596
Database links:
Entrez Gene: 23596 Human
Entrez Gene: 13603 Mouse
Omim: 606695 Human
SwissProt: Q9H1Y3 Human
SwissProt: Q9WUK7 Mouse
Unigene: 409081 Human
Unigene: 32744 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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