产品详情
白屈菜红碱
分析标准品,>98%
Product Name: Chelerythrine chloride
| 别名: | 白屈菜红碱 ;白屈菜赤碱，白屈菜季铵碱 |
| CAS号: | 34316-15-9 |
| 分子式: | C21H18ClNO4 |
| 分子量: | 383.83 |
白屈菜红碱
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| 用途: | 对某些真菌、细菌和病毒有抑制作用，但对神经、心脏等有毒害，可引起麻痹、心脏抑制，甚至导致死亡。 |
| 熔点: | 195-205°C |
| 生化和生理学机理: | 白屈菜红碱Chelerythrine is potent, cell-permeable inhibitor of protein kinase C (IC50 = 660 nM). competitive with respect to the phosphate acceptor and non-competitive with respect to ATP. Chelerythrine has a wide range of biological activities, including antiplatelet, anti-inflammatory, antibacterial and antitumor effects. Activates MAPK pathways, independent of PKC inhibition. Inhibits binding of BclXL to Bak (IC50 = 1.5 μM) or Bad proteins and stimulates apoptosis. |