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上海沪震生物科技有限公司
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英文名称    Ferredoxin Reductase    

中文名称    铁氧化还原蛋白还原酶抗体    

别    名    adrenodoxin reductase; ADRO_HUMAN; ADXR; AR; FDXR; Ferredoxin NADP(+) reductase; Ferredoxin reductase; Ferredoxin--NADP(+) reductase; mitochondrial; NADPH adrenodoxin oxidoreductase mitochondrial; NADPH:adrenodoxin oxidoreductase.    

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  细胞生物  免疫学  信号转导      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Horse,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 铁氧化还原蛋白还原酶抗体(石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    50kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human Ferredoxin Reductase    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

铁氧化还原蛋白还原酶抗体产品介绍    background:

Adrenodoxin Reductase (ADX Reductase) is a mitochondrial flavoprotein that receives electrons from NADPH and thereby initiates the electron-transport chain serving mitochondrial cytochromes P450. ADX Reductase participates in cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-? hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney and sterol C-27 hydroxylation in the liver. Alternate splicing of ADX Reductase produces two isoforms. Human ADX Reductase maps to human chromosome 17q24-q25.

Function:
Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.

Subunit:
Monomer. Interacts directly with FDX1.

Subcellular Location:
Mitochondrion matrix.

Similarity:
Belongs to the ferredoxin--NADP reductase type 1 family.

Database links:

Entrez Gene: 2232 Human

Entrez Gene: 14149 Mouse

Entrez Gene: 79122 Rat

Omim: 103270 Human

SwissProt: P22570 Human

SwissProt: Q61578 Mouse

SwissProt: P56522 Rat

Unigene: 69745 Human

Unigene: 4719 Mouse

Unigene: 10860 Rat


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

铁氧化还原蛋白还原酶抗体

hz-4566R Shadow/shadow of prion protein(CT)  新朊蛋白抗体(C端)

hz-1175R SHBG  性激素结合球蛋白抗体

hz-3572R SHC  SH2结构域转化蛋白1抗体

hz-3410R phospho-SHC(Ser36)  磷酸化SH2结构域转化蛋白1抗体

hz-3411R phospho-SHC(Tyr349)  磷酸化SH2结构域转化蛋白1抗体

hz-3412R phospho-SHC (Tyr427)  磷酸化SH2结构域转化蛋白1抗体

hz-3413R phospho-SHC (Tyr317)  磷酸化SH2结构域转化蛋白1抗体

hz-3414R phospho-SHC(Tyr239/240)  磷酸化SH2结构域转化蛋白1抗体

hz-0882R Shiga-like toxin IIe variant subunit A  大肠杆菌志贺样毒素Ⅱ型突变体(O139菌型)抗体

hz-1544R Shh  Shh信号转导通路膜蛋白受体抗体

hz-2699R OMPC  大肠杆菌外膜孔道蛋白C抗体

hz-3567R SHIP1  SH2结构含磷酸肌醇SHIP1抗体

hz-3398R Phospho-SHIP1 (Tyr1020)  磷酸化SH2结构含磷酸肌醇SHIP1抗体

hz-1129R SHP-1  造血细胞磷酸酶抗体

hz-3629R PTPN4/MEG1  蛋白酪氨酸磷酸酶非受体型4抗体

hz-1233R PTPN11  蛋白酪氨酸磷酸酶2抗体

hz-3399R Phospho-INPPL1(Tyr1135)  肌醇聚磷酸盐磷酸酶样蛋白1抗体

hz-3402R Phospho-INPPL1(Ser576)  肌醇聚磷酸盐磷酸酶样蛋白1抗体

hz-3403R Phospho-PTPN11(Tyr542)  磷酸化蛋白酪氨酸磷酸酶2抗体

hz-3404R Phospho-INPPL1(Tyr986/987)  肌醇聚磷酸盐磷酸酶样蛋白1抗体

hz-3405R Phospho-PTPN11 (Tyr584)  磷酸化蛋白酪氨酸磷酸酶2抗体

hz-5434R Phospho-SHP2/SHIP2(Tyr477)  磷酸化蛋白酪氨酸磷酸酶2抗体

hz-5638R Phospho-SHP2/SHIP2(Tyr81)  磷酸化蛋白酪氨酸磷酸酶2抗体

hz-3596R SIAH1  泛素连接酶Siah1抗体

hz-3634R SIAH2  泛素连接酶Siah2

hz-1130R SIP1/ZEB-2  运动神经元存活蛋白结合蛋白1抗体

hz-5576R phospho-PTPN6(Tyr476)  磷酸化蛋白酪氨酸磷酸酶1C抗体

hz-4187R ZEB1/AREB6  负调控因子白细胞介素2抗体

hz-5577R phospho-PTPN6(Tyr536)  磷酸化蛋白酪氨酸磷酸酶1C抗体

hz-5578R phospho-PTPN6(Ser591)  磷酸化蛋白酪氨酸磷酸酶1C抗体

hz-4158R PTPN6/SHP1  蛋白酪氨酸磷酸酶1C抗体

hz-0921R SIRT1  沉默调节蛋白1抗体

hz-3416R Phospho-SirT1 (Ser27)  磷酸化沉默调节蛋白1抗体