产品详情
白细胞介素-10受体a抗体
产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
白细胞介素-10受体a抗体产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
白细胞介素-10受体a抗体产品说明
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq].
mol wt:60kDa
Other Aliases:
Interleukin-10 Receptor; CD210; CDW210A; CDw210a antigen; HIL 10R; HIL10R; IL 10R 1; IL 10R A; IL 10R; IL 10R1; IL10R; IL10R1; Interleukin 10 receptor alpha; Interleukin 10 receptor alpha chain
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