产品详情
英文名称 PI14
中文名称 蛋白酶抑制剂14抗体
别 名 MEPI; Myoepithelium derived serine protease inhibitor; Pancpin; Pancreas specific protein TSA2004; Peptidase inhibitor 14; PI 14; PI14; Protease inhibitor 14; Serine (or cysteine) proteinase inhibitor clade I (neuroserpin) member 2; Serine (or cysteine) proteinase inhibitor clade I (pancpin) member 2; Serpin I2; Serpin peptidase inhibitor clade I (pancpin) member 2; TSA2004; SPI2_HUMAN; SERPINI2.
蛋白酶抑制剂14抗体
说 明 书 0.2ml
研究领域 肿瘤 心血管 细胞生物 免疫学
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Horse,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 44kDa
细胞定位 分泌型蛋白
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SERPINI2/PI14
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
蛋白酶抑制剂14抗体产品介绍 background:
SERPINI2 is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. It may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.
Subcellular Location:
Secreted
Tissue Specificity:
Expressed in pancreas and adipose tissues.
Similarity:
Belongs to the serpin family.
Database links:
Entrez Gene: 5276 Human
Entrez Gene: 67931 Mouse
Entrez Gene: 171149 Rat
Omim: 605587 Human
SwissProt: O75830 Human
SwissProt: Q9JK88 Mouse
Unigene: 445555 Human
Unigene: 259446 Mouse
Unigene: 54500 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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