产品详情
英文名称 SPDYA
中文名称 细胞周期G2/M期快速诱导蛋白SPDYA抗体
别 名 hSpy/Ringo A; Rapid inducer of G2/M progression in oocytes A; RINGO A; RINGO3; SPDY1; Speedy A; Speedy homolog 1 (Drosophila); Speedy homolog A; Speedy homolog A (Xenopus laevis); Speedy-1; SPY1; MGC110856; MGC57218; OTTHUMP00000082662; OTTHUMP00000082663; OTTHUMP00000082664.
细胞周期G2/M期快速诱导蛋白SPDYA抗体
说 明 书 0.2ml
研究领域 细胞生物 细胞周期蛋白 激酶和磷酸酶 表观遗传学
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
细胞定位 细胞核
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SPDYA
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
细胞周期G2/M期快速诱导蛋白SPDYA抗体 产品介绍 background:
SPDYA (speedy homolog A (Drosophila)) regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. SPDYA can activate CDK2 without promoting CDK2 phosphorylation. SPDYA mediates cell survival during the DNA damage process through activation of CDK2.
Function:
Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1, CDK2 and CDKN1B/KIP1. Can activate CDK2 without promoting CDK2 phosphorylation. Mediates cell survival during the DNA damage process through activation of CDK2.
Subunit:
Interacts with CDK1, CDK2 and CDKN1B/KIP1. Found in a complex with both CDK2 and CDKN1B/KIP1.
Subcellular Location:
Nucleus.
Tissue Specificity:
Highly expressed in testis. Expressed at a low level in wide range of tissues including bone marrow, brain, heart, kidney, colon, liver, placenta, spleen, skeletal muscle, salivary gland, thyroid gland, thymus, trachea and uterus. Expressed at a slightly higher level in adrenal gland, cerebellum, small intestine, lung, prostate and trachea. Expression is cell cycle-dependent, being restricted to cells in G1/S phase.
Similarity:
Belongs to the Speedy/Ringo family.
Database links:
UniProtKB/Swiss-Prot: Q5MJ70.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞周期G2/M期快速诱导蛋白SPDYA抗体
hz-7643R ARTS1 脂肪细胞源性亮氨酸氨基肽酶抗体(血管内皮细胞生长因子诱导蛋白)
hz-7644R NSPL2/RTN3 神经内分泌特异性蛋白2抗体
hz-7645R TID1/HCA57 肝癌相关抗原57抗体
hz-7646R FIS1/TTC11 线粒体裂变1蛋白抗体
hz-7647R VDAC3 线粒体外膜孔蛋白3抗体(电压依赖阴离子通道蛋白3)
hz-7648R DFFB DNA断裂因子抗体(蛋白酶激活脱氧核糖核酸酶)
hz-7649R CIDE A DNA断裂因子相似蛋白A抗体
hz-7650R CIDE B DNA断裂因子相似蛋白B抗体
hz-7651R DNase I 脱氧核糖核酸酶1抗体
hz-7652R DNase II 脱氧核糖核酸酶2抗体
hz-7653R DNase gamma 脱氧核糖核酸酶γ抗体
hz-7654R TIP30 TIP30蛋白抗体
hz-7655R AMID/AIFM2 线粒体凋亡诱导因子2抗体
hz-7656R ATAD5 染色体脆弱性相关基因抗体
hz-7657R BAT3/BAG6 Bcl2相关抗凋亡基因6抗体
hz-7658R CTNNBL1/Beta catenin like 1 β连环蛋白样蛋白1抗体
hz-7659R DATF1 死亡相关转录因子1抗体
hz-7660R TFDP2/DP2 转录因子E2F二聚体蛋白2抗体
hz-7661R EAF2 睾酮调节细胞凋亡诱导和肿瘤抑制基因抗体
hz-7662R FLI1 尤文肉瘤FLI1蛋白抗体
hz-7663R MDMX MDM2样P53蛋白结合抗体
hz-7664R TMUB1 跨膜和泛素样结构域蛋白1抗体
hz-7665R NUP50 核孔蛋白50抗体
hz-7666R PDCD2L/MGC13096 程序性细胞死亡2抗体
hz-7667R SLTM 转绿调节因子SLTM抗体
hz-7668R GPR65 G蛋白偶联受体65抗体
hz-7669R AX2R/LOC389289 膜粘连蛋白2受体抗体
hz-7671R NADE/NGFRAP1 神经生长因子受体相关蛋白1抗体
hz-7672R NRH2 死亡结构域蛋白NRH2抗体
hz-7673R PGRPS 肽聚糖识别蛋白1抗体
hz-7674R Porimin 前细胞胀亡受体诱导膜损伤蛋白抗体
hz-7676R TRAF7 肿瘤坏死因子受体相关因子7抗体