产品详情
英文名称 SKA3
中文名称 纺锤体和着丝粒相关蛋白3抗体
别 名 C13orf3; RAMA1; SKA3; SKA3_HUMAN; Spindle and kinetochore associated complex subunit 3; Spindle and kinetochore-associated protein 3.
纺锤体和着丝粒相关蛋白3抗体
说 明 书 0.2ml
研究领域 细胞生物 细胞周期蛋白 细胞分化
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, Sheep,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
细胞定位 细胞核 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SKA3
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
纺锤体和着丝粒相关蛋白3抗体 产品介绍 background:
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule-stimulated oligomerization.
Function:
Component of the SKA1 complex, a microtubule-bindingsubcomplex of the outer kinetochore that is essential for properchromosome segregation. The SKA1 complex is a direct component ofthe kinetochore-microtubule interface and directly associates withmicrotubules as oligomeric assemblies. The complex facilitates theprocessive movement of microspheres along a microtubule in adepolymerization-coupled manner. In the complex, it mediates themicrotubule-stimulated oligomerization.
Subunit:
Component of the SKA1 complex, composed of SKA1, SKA2 andSKA3. The core SKA1 complex is composed of 2 SKA1-SKA2heterodimers, each heterodimer interacting with a molecule of theSKA3 homodimer. The core SKA1 complex associates with microtubulesand forms oligomeric assemblies. Interacts directly with SKA1.
Subcellular Location:
Cytoplasm, cytoskeleton, spindle.Chromosome, centromere, kinetochore. Note=Localizes to the outerkinetochore and spindle microtubules during mitosis in a NDC80complex-dependent manner.
Similarity:
Belongs to the SKA3 family.
Database links:
UniProtKB/Swiss-Prot: Q8IX90.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
纺锤体和着丝粒相关蛋白3抗体
hz-7760R Factor VII light chain 凝血因子VII
hz-7761R Myosin VIIa/DFNB2 肌球蛋白7a/常染色体隐性耳聋蛋白2抗体
hz-7762R Factor X 凝血因子10抗体
hz-7763R NIR2 膜磷脂转移蛋白1抗体
hz-7764R NUSAP1 核仁和纺锤体相关蛋白1抗体
hz-7765R RAB35 RAS相关蛋白癌基因Rab35抗体
hz-7766R RACGAP1 Rho GTP酶激活蛋白GAP抗体
hz-7767R phospho-RACGAP1(Ser387) 磷酸化Rho GTP酶激活蛋白GAP抗体
hz-7768R RCC2 染色体浓缩调节蛋白2抗体
hz-7769R SEPT1 细胞分化蛋白SEP1抗体
hz-7770R SEPT10 细胞分化蛋白SEPT10抗体
hz-7771R SEPT12 细胞分化蛋白SEPT12抗体
hz-7772R SEPT14 细胞分化蛋白SEPT14抗体
hz-7773R SPECC1L 细胞质和纺锤体机化蛋白A抗体
hz-7774R Septin 3 神经元特异性蛋白3抗体
hz-7776R UCHL5IP 泛素羧基末端水解酶5互相作用蛋白1抗体
hz-7777R VPS4a 液泡分选蛋白4抗体
hz-7778R APC5 细胞分裂周期蛋白5抗体
hz-7779R BRD7 鼻咽癌相关转录调节蛋白抗体
hz-7780R BRRN1/CAPH 染色体相关蛋白H抗体
hz-7781R CDC123/C10orf7 细胞分裂周期蛋白CDC123抗体
hz-7782R CCDC16/zinc finger protein 830 锌指蛋白830抗体
hz-7783R CDC20B 细胞分裂周期蛋白20B抗体
hz-7784R ccnb1ip1 周期蛋白B1结合蛋白1抗体
hz-7785R CDC45L 细胞分裂周期调控蛋白45抗体
hz-7786R CDCA2 细胞分裂周期蛋白2抗体
hz-7787R CEP152 中心体蛋白152抗体
hz-7788R CEP76 中心体蛋白质76抗体
hz-7789R CHMP1B 染色质修饰蛋白1B抗体
hz-7790R CIRBP 冷诱导RNA结合蛋白抗体