产品详情
Product Name: (-)-Huperzine A
别名: | (-)-石杉碱甲 |
CAS号: | 102518-79-6 |
分子式: | C15H18N2O |
分子量: | 242.32 |
MDL号: | MFCD01714949 |
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用途: | 石杉碱甲不仅通过抑制胆碱酯酶活性,还可以通过影响自由基系统,降低生长抑素、细胞内[Ca2+]、谷氨酸含量,提高钙调蛋白(CaM)和钙调蛋白的信使核糖核酸(CaM mRNA)表达水平等多种药理机制,提高认知功能和学习记忆能力。 |
特定比重: | 1.2 |
贮存: | 贮存温度-20℃ |
可溶性: | 易溶于氯仿,溶于甲醇、乙醇,微溶于水 |
生化和生理学机理: | Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD). Huperzine A exhibited protective effects against d-gal-induced hepatotoxicity and inflamm-aging by inhibiting AChE activity and via the activation of the cholinergic anti-inflammatory pathway. The huperzine A mechanism might be involved in the inhibition of DAMPs-mediated NF-κB nuclear localization and activation. Huperzine A is a potential therapeutic agent for Alzheimer's disease. |
A0096-7L-赖氨酸甲酯盐酸盐/L-赖氨酸甲酯二盐酸盐/H-Lys-OMe.2HCl特纯,98.0%
A0096-8L-赖氨酸乙酯二盐酸盐/H-Lys-OEt?2HCl特纯,98.0%
A0096-9L-甲硫氨酸乙酯盐酸盐/L-蛋氨酸乙酯盐酸盐/L-Methionine ethyl ester hydrochloride特纯,99.0%
A0096-10L-苯丙氨酸甲酯盐酸盐/L-苯基丙氨酸甲酯盐酸盐/H-Phe-OMe?HCl特纯,98.0%
A0096-11L-苯丙氨酸乙酯盐酸盐/L-苯基丙氨酸乙酯盐酸盐/H-Phe-OEt.HCl特纯,99.0%
A0096-12L-苯甘氨酸甲酯盐酸盐/(S)-(+)-2-苯基甘氨酸甲酯盐酸盐/L-α-苯甘氨酸甲酯盐酸盐/L-苯基甘氨酸甲酯盐酸盐/L-Phenylglycine methyl ester?HCl特纯,97.0%
A0096-13L-苯甘氨酸乙酯盐酸盐/(R)-α-氨基苯乙酸乙酯氢氯化物/L-phenylglycine ethyl ester?HCl特纯,98.5%
A0096-14L-脯氨酸甲酯盐酸盐/L-卟啉甲酯盐酸盐/吡咯烷-2-碳酸甲酯盐酸盐/H-Pro-OMe?HCl特纯,98.5%
A0096-15L-脯氨酸苄酯盐酸盐/H-Pro-OBzl?HCl特纯,98.0%
A0096-16L-羟脯氨酸甲酯盐酸盐/反式-4-羟基-L-脯氨酸甲酯盐酸盐/(2S,4R)-4-羟基-L-脯氨酸甲酯盐酸盐/H-Hyp-OMe?HCl特纯,98.0%
A0096-17L-苏氨酸甲酯盐酸盐/H-Thr-OMe?HCl特纯,98.0%
A0096-18L-色氨酸甲酯盐酸盐/H-Trp-OMe?HCl特纯,98.0%
A0096-19L-酪氨酸甲酯/H-Tyr-Ome特纯,98.5%
A0097L-正缬氨酸/L-2-氨基戊酸/L-原缬氨酸/L-正穿心排草氨基酸/L-(+)-2-氨基戊酸/L-NorvalineBR,99%
A0098D-正缬氨酸/D-2-氨基戊酸/D-原缬氨酸/D-正穿心排草氨基酸/R-2-氨基戊酸/D-NorvalineBR,99%
A0099D-正亮氨酸/D-正白氨酸/D-2-氨基己酸/D-NorleucineBR,98%
A0100L-正亮氨酸/L-正白氨酸/L-原亮氨酸/L-原闪白氨基酸/L-2-氨基正己酸/L-2-氨基己酸/L-NorleucineBR,99%
A0101DL-正亮氨酸/DL-正白氨酸/DL-正闪白氨基酸/DL-己氨酸/DL-原亮氨酸/DL-2-氨基正己酸/2-氨基己酸/DL-NorleucineBR,98.5%
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A0104D-组氨酸/D-2-氨基-3-(4-咪唑基)丙酸/D-组织氨酸/D-甘噁啉-5-闪氨酸/D-甘恶啉-5-丙氨酸/D-组织氨基酸/D-HistidineBR,99%
A0105DL-组氨酸/(±)-2-氨基-3-(4-咪唑基)丙酸/DL-2-氨基-3-(1H-咪唑-4-基)丙酸/DL-组织氨基酸/DL-HistidineBR,99%
A0105-1DL-组氨酸盐酸盐/DL-氢氯组氨酸/DL-α-氨基-β-(4-咪唑基)丙酸单盐酸盐/DL-Histidine HCL H2OBR,99%
A0105-2D-组氨酸盐酸盐/D-氢氯组氨酸/D-α-氨基-β-(4-咪唑基)丙酸单盐酸盐/D-Histidine monohydrochloride monohydrateBR,99%
A0106L-组氨酸盐酸盐/盐酸组氨酸/L-氢氯组氨酸/L-Histidine HCLBR,99%
A0106-1L-组氨酸盐酸盐一水物/盐酸组氨酸/L-氢氯组氨酸一水物/L-Histidine HCL H2OBR,99%
A0107BOC-Nim-苄基-L-组氨酸/BOC-Nim-benzyl-L-Histidine特纯,98%
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A0109D-丝氨酸/D-蚕丝氨基酸/D-2-氨基-3-羟基丙酸/D-β-羟基丙氨酸/D-SerineBR,99%
A0110DL-丝氨酸/DL-蚕丝氨基酸/DL-2-氨基-3-羟基丙酸/DL-β-羟基丙氨酸/DL-SerineBR,99%
A0111N-乙酰-DL-丝氨酸/N-Acetyl-DL-SerineBR,98%
A0112D-环丝氨酸/D-4-氨基-3-异噁唑烷酮/环丝氨酸/(R)-(+)-环丝氨酸/D-CycoloserineBR,98%,900μg/mg