产品详情
英文名称 WASF3
中文名称 Verprolin同源结构域包含蛋白3抗体
别 名 KIAA0900; Protein WAVE-3; Protein WAVE3; SCAR3; Verprolin homology domain containing protein 3; Verprolin homology domain-containing protein 3; WASF3; WASF3_HUMAN; WASP family protein member 3; WAVE3; Wiskott Aldrich syndrome protein family member 3; Wiskott-Aldrich syndrome protein family member 3.
Verprolin同源结构域包含蛋白3抗体
说 明 书 0.1ml 0.2ml
研究领域 细胞生物 信号转导 结合蛋白 G蛋白偶联受体 细胞骨架 G蛋白信号
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
细胞定位 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human WASF3
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Verprolin同源结构域包含蛋白3抗体产品介绍 background:
Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton.
Function:
Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.
Subunit:
Binds actin and the Arp2/3 complex.
Subcellular Location:
Cytoplasm, cytoskeleton.
Tissue Specificity:
Expressed in ovary and brain.
Post-translational modifications:
Phosphorylation by ABL1 promotes lamellipodia formation and cell migration.
Similarity:
Belongs to the SCAR/WAVE family.
Contains 1 WH2 domain.
Gene ID:
10810
Database links:
Entrez Gene: 10810 Human
Entrez Gene: 245880 Mouse
Omim: 605068 Human
SwissProt: Q9UPY6 Human
SwissProt: Q8VHI6 Mouse
Unigene: 635221 Human
Unigene: 472750 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Verprolin同源结构域包含蛋白3抗体
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