产品详情
英文名称 TSPY1
中文名称 睾丸特异定蛋白质编码Y1抗体
别 名 DYS14; pJA 923; pJA923; Testis specific protein Y linked 1; Testis specific Y encoded protein 1; TSPY 1; TSPY; TSPY1_HUMAN.
睾丸特异定蛋白质编码Y1抗体
说 明 书 0.1ml 0.2ml
研究领域 肿瘤 细胞生物 发育生物学 染色质和核信号 干细胞
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
细胞定位 细胞核 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TSPY1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
睾丸特异定蛋白质编码Y1抗体产品介绍 background:
The function of this protein is unknown. TSPY genes are located on the Y-chromosome of several mammalian species. TSPY encodes a testis-specific protein 1, which probably acts as nucleosome-binding transcription factor. Homology with the SET/NAP/DENTT oncogene family suggest a role in spermatogonic cell division and seminal oncogenesis.
Function:
May be involved in sperm differentiation and proliferation.
Subcellular Location:
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Also found in nucleus.
Tissue Specificity:
Specifically expressed in testicular tissues. Isoform 1 and isoform 2 are expressed in spermatogonia and spermatocytes. Found in early testicular carcinoma in situ, spermatogonial cells in testicular tissues of 46,X,Y female and in prostate cancer cell lines.
Post-translational modifications:
Phosphorylated.
Similarity:
Belongs to the nucleosome assembly protein (NAP) family.
Database links:
UniProtKB/Swiss-Prot: Q01534.4
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
睾丸特异定蛋白质编码Y1抗体
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