产品详情
英文名称 SPATS2
中文名称 富含丝氨酸精子发生相关蛋白2抗体
别 名 Nbla00526; p59scr; SCR59; Serine-rich spermatocytes and round spermatid 59 kDa protein; SPAS2_HUMAN; SPATA10; Spats2; Spermatogenesis-associated serine-rich protein 2.
富含丝氨酸精子发生相关蛋白2抗体
说 明 书 0.2ml
研究领域 细胞生物 免疫学 发育生物学
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
细胞定位 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SPATS2
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
富含丝氨酸精子发生相关蛋白2抗体产品介绍 background:
SPATS2 is a 545 amino acid cytoplasmic protein that belongs to the SPATS2 family. The gene encoding SPATA10 maps to human chromosome 12q13.12 and mouse chromosome 15 F1. Chromosome 12 makes up about 4.5% of the human genome and is linked to a number of skeletal deformities, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster, which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster, encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms which vary in severity depending on the extent of mosaicism. It is most severe in cases of complete trisomy.
Subunit:
Belongs to the SPATS2 family.
Subcellular Location:
Cytoplasm.
Database links:
Entrez Gene: 65244 Human
Omim: 611667 Human
SwissProt: Q86XZ4 Human
Unigene: 654826 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
富含丝氨酸精子发生相关蛋白2抗体
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