英文名称    Syndecan-1    

中文名称    多配体蛋白聚糖1抗体    

别    名    SDC1; SDC; SYND1; Syndecan I; SyndecanI; Syndecan-I; syndecan; Sdc1; Syndecan1, Syndecan-1; AA408134; AA409076; Sstn; syn-1; CD 138; CD138 antigen; Heparan sulfate proteoglycan fibroblast growth factor receptor; SDC 1; Syndecan1 precursor; SDC1_HUMAN.    

多配体蛋白聚糖1抗体     

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  神经生物学  细胞膜受体  细胞粘附分子  细胞表面分子  糖蛋白  上皮细胞  内皮细胞      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    34kDa    

细胞定位    细胞膜 分泌型蛋白     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CD138    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

多配体蛋白聚糖1抗体 产品介绍    background:
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008].

Function:
Cell surface proteoglycan that bears both heparin sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.

Subunit:
Interacts with CDCP1.

Subcellular Location:
Membrane; Single-pass type I membrane protein. Secreted. Note=Shedding of the ectodomain produces a soluble form.

Post-translational modifications:
Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3.

Similarity:
Belongs to the syndecan proteoglycan family.

Gene ID:
6382

Database links:

Entrez Gene: 6382 Human

Entrez Gene: 20969 Mouse

Entrez Gene: 25216 Rat

Omim: 186355 Human

SwissProt: P18827 Human

SwissProt: P18828 Mouse

SwissProt: P26260 Rat

Unigene: 224607 Human

Unigene: 665958 Human

Unigene: 2580 Mouse

Unigene: 11176 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

多配体蛋白聚糖1抗体 

hz-0297M-PE Mouse Anti-human IgG/PE  PE标记的小鼠抗人IgG

hz-0297M-PE-hzy3 Mouse Anti-human IgG/PE-Cy3  PE-Cy3标记的小鼠抗人IgG

hz-0297M-PE-hzY5 Mouse Anti-human IgG/PE-CY5  PE-CY5标记的小鼠抗人IgG

hz-0297M-APhz Mouse Anti-human IgG/APC  APC标记的小鼠抗人IgG

hz-0297M-FIThz Mouse Anti-human IgG/FITC  FITC标记的小鼠抗人IgG

hz-0297M-RBIThz Mouse Anti-human IgG/RBITC  罗丹明标记的小鼠抗人IgG

hz-0297M-Gold Mouse Anti-human IgG/Gold  胶体金标记的小鼠抗人IgG

hz-0345M-FIThz Mouse Anti-human IgM/FITC  FITC标记的小鼠抗人IgM

hz-0345M-hzy3 Mouse Anti-human IgM/Cy3  Cy3标记的小鼠抗人IgM

hz-0345M-hzy5 Mouse Anti-human IgM/Cy5  Cy5标记的小鼠抗人IgM

hz-0345M-hzy5.5 Mouse Anti-human IgM/Cy5.5  Cy5.5标记的小鼠抗人IgM

hz-0345M-PE-hzy3 Mouse Anti-human IgM/PE-Cy3  PE-Cy3标记的小鼠抗人IgM

hz-0345M-PE-hzY5 Mouse Anti-human IgM/PE-CY5  PE-CY5标记的小鼠抗人IgM

hz-0345M-APhz Mouse Anti-human IgM/APC  APC标记的小鼠抗人IgM

hz-0345M-AF350 Mouse Anti-human IgM/Alexa Fluor 350  Alexa Fluor 350标记的小鼠抗人IgM

hz-0345M-AF488 Mouse Anti-human IgM/Alexa Fluor 488  Alexa Fluor 488标记的小鼠抗人IgM

hz-0345M-AF555 Mouse Anti-human IgM/Alexa Fluor 555  Alexa Fluor 555标记的小鼠抗人IgM

hz-0345M-AF647 Mouse Anti-human IgM/Alexa Fluor 647  Alexa Fluor 647标记的小鼠抗人IgM

hz-0345M-PE-hzy5.5 Mouse Anti-human IgM/PE-Cy5.5  PE-Cy5.5标记的小鼠抗人IgM

hz-0345M-PE-hzy7 Mouse Anti-human IgM/PE-Cy7  PE-Cy7标记的小鼠抗人IgM

hz-0345M-RBIThz Mouse Anti-human IgM/RBITC  罗丹明标记的小鼠抗人IgM

hz-0345M-Bio Mouse Anti-human IgM/Bio  生物素标记的小鼠抗人IgM

hz-0345M-HRP Mouse Anti-human IgM/HRP  辣根过氧化物酶标记的小鼠抗人IgM

hz-0345M-Gold Mouse Anti-human IgM/Gold  胶体金标记的小鼠抗人IgM

hz-0345M-AP Mouse Anti-human IgM/AP  碱性磷酸酶（AP）标记的小鼠抗人IgM

hz-0345M-hzy7 Mouse Anti-human IgM/Cy7  Cy7标记的小鼠抗人IgM

hz-0345M-PE Mouse Anti-human IgM/PE  PE标记的小鼠抗人IgM

hz-0294M-HRP Mouse Anti-Goat IgG/HRP  辣根过氧化物酶标记的小鼠抗羊IgG

hz-0294M-RBIThz Mouse Anti-Goat IgG/RBITC  罗丹明标记的小鼠抗羊IgG

hz-0294M-Bio Mouse Anti-Goat IgG/Bio  生物素标记的小鼠抗羊IgG

hz-0294M-Gold Mouse Anti-Goat IgG/Gold  胶体金标记的小鼠抗羊IgG

hz-0294M-hzy3 Mouse Anti-Goat IgG/Cy3  Cy3标记的小鼠抗羊IgG

hz-0294M-hzy5 Mouse Anti-Goat IgG/Cy5  Cy5标记的小鼠抗羊IgG

hz-0294M-hzy5.5 Mouse Anti-Goat IgG/Cy5.5  Cy5.5标记的小鼠抗羊IgG

hz-0294M-hzy7 Mouse Anti-Goat IgG/Cy7  Cy7标记的小鼠抗羊IgG

hz-0294M-PE Mouse Anti-Goat IgG/PE  PE标记的小鼠抗羊IgG

hz-0294M-PE-hzy3 Mouse Anti-Goat IgG/PE-Cy3  PE-Cy3标记的小鼠抗羊IgG