产品详情
英文名称 Relaxin 1
中文名称 松弛肽/松弛素抗体
别 名 H1 antibody Preprorelaxin H1; PreprorelaxinH1; Prorelaxin; Prorelaxin H1; ProrelaxinH1; Relaxin 1 (H1); Relaxin H1; Relaxin1; Relaxin-1; RelaxinH1; RLN 1; RLN1; RLX H1; RLXH 1; RLXH1; REL1_HUMAN.
松弛肽/松弛素抗体
说 明 书 0.2ml
研究领域 细胞生物 信号转导 生长因子和激素
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 18kDa
细胞定位 分泌型蛋白
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Relaxin 1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
松弛肽/松弛素抗体产品介绍 background:
Relaxin is a peptide hormone produced by the corpora lutea of ovaries during pregnancy in many mammalian species, including man. The secretion of the hormone into the blood stream just before parturition results in a marked softening and lengthening of the pubic symphysis and a softening of the cervix, which facilitates the birth process. By inhibiting uterine contractions, relaxin may influence the timing of parturition. Like insulin, relaxin consists of two peptide chains, A and B, covalently linked by disulfide bonds. By further analogy to insulin, the two peptides are synthesized as a single-chain precursor polypeptide with the B chain at the NH2-terminus.
Function:
Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.
Subunit:
Heterodimer of a B chain and an A chain linked by two disulfide bonds.
Subcellular Location:
Secreted
Tissue Specificity:
Prostate. Not expressed in placenta, decidua or ovary.
Gene ID:
6013
Database links:
Entrez Gene: 6013 Human
Entrez Gene: 19773 Mouse
Entrez Gene: 25616 Rat
Omim: 179730 Human
SwissProt: P04808 Human
SwissProt: P47932 Mouse
SwissProt: P01347 Rat
Unigene: 368996 Human
Unigene: 9830 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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