产品详情
英文名称 parathyroid hormone
中文名称 甲状旁腺激素抗体
别 名 hPTH; Parathormone; Parathyrin; Parathyroid hormone 1; Parathyroid hormone; PTH; PTH1; PTH1 receptor; PTH1R; PTHR; PTHR1; PTHY_HUMAN.
甲状旁腺激素抗体
说 明 书 0.1ml 0.2ml
研究领域
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 4kDa
细胞定位 分泌型蛋白
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human parathyroid hormone
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
甲状旁腺激素抗体产品介绍 Function:
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
Subunit:
Interacts with PTH1R (via N-terminal extracellular domain).
Subcellular Location:
Secreted.
DISEASE:
Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Similarity:
Belongs to the parathyroid hormone family.
Gene ID:
5741
Database links:
Entrez Gene: 280903 Cow
Entrez Gene: 403986 Dog
Entrez Gene: 5741 Human
Entrez Gene: 19226 Mouse
Entrez Gene: 399502 Pig
Entrez Gene: 24694 Rat
Omim: 168450 Human
SwissProt: P01268 Cow
SwissProt: P52212 Dog
SwissProt: P01270 Human
SwissProt: P01269 Pig
SwissProt: P04089 Rat
Unigene: 37045 Human
Unigene: 284168 Mouse
Unigene: 9768 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
甲状旁腺激素抗体
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