产品详情
抗诱捕受体3抗体产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
抗诱捕受体3抗体产品介绍
DcR3是一个新发现的具有免疫抑制作用的分子,也属于肿瘤坏死因子受体超家族的成员。DcR3通过拮抗Fas/FasL、LIGHT/LTβR来发挥作用,在肿瘤及免疫性疾病中发挥重要作用。
Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively. Unlike DcR1and DcR2, DcR3 is a soluble rather than a membraneassociated molecule. DcR3 binds to FasL and LIGHT andinhibits FasL and LIGHT induced apoptosis. DcR3 transcript is expressed in a number of lung and coloncarcinomas and in some normal tissues.
mol wt:33kDa
Other Aliases:
Decoy receptor 3; Tumor necrosis factor receptor superfamily member 6B; Decoy receptor for Fas ligand; M68
抗诱捕受体3抗体
hz-7703R TSPYL5 睾丸特异性Y蛋白样5抗体
hz-7705R UBTD1 泛素结构域蛋白1抗体
hz-3025R phospho-AMPK alpha-1(Ser485+Ser491) 磷酸化腺苷单磷酸活化蛋白激酶α1抗体
hz-7706R VRK1 牛痘病毒相关激酶1抗体(丝氨酸/苏氨酸蛋白激酶VRK1)
hz-5551R phospho-AMPK alpha-1/PRKAA1(Thr198) 磷酸化腺苷单磷酸活化蛋白激酶α1抗体
hz-7707R ZBTB2 锌指蛋白437抗体
hz-2771R PRKAA2/AMPK alpha 2 腺苷单磷酸活化蛋白激酶α2抗体
hz-7708R ZNF415 锌指蛋白415抗体
hz-7709R Retinoic acid induced 17 维甲酸诱导蛋白17抗体
hz-7710R CENPP 着丝粒蛋白P抗体
hz-7711R PCNT/Pericentrin 中心粒周蛋白抗体
hz-7712R Importin4/RanBP4 核蛋白4抗体(Ran结合蛋白4)
hz-7713R MIS12 染色体及有丝分裂蛋白MIS12抗体
hz-7714R CDCA1/Nuf2 细胞分裂周期相关蛋白1抗体
hz-7715R Importin 9/RanBP9 核蛋白9抗体(Ran结合蛋白M)
hz-7716R SPC25 纺锤体极点构成蛋白25抗体
hz-7717R CDCA5/Sororin 细胞分裂周期相关蛋白5抗体
hz-7718R CAPD2/CNAP1 染色体相关蛋白2抗体
hz-7719R KRG2/DDX11 角质细胞生长因子调节蛋白2抗体
hz-7720R DSCC1 DSCC1蛋白抗体
hz-5285R phospho-CARM1(Ser228) 磷酸化蛋白精氨酸N甲基4抗体
hz-5575R phospho-PRKAA2(Ser173) 腺苷单磷酸活化蛋白激酶α2抗体
hz-7721R CAPG2/NCAPG2 染色体相关蛋白2抗体
hz-7722R APRIN/PDS5B 雄激素诱导增殖抑制蛋白抗体
hz-7723R REC8 减数分裂重组蛋白家族REC8抗体
hz-7724R SA1/Nuclear protein stromal antigen 1 粘结蛋白SA1抗体
hz-7725R SA2 粘结蛋白SA2抗体
hz-7726R phospho-REC8(Ser251) 磷酸化减数分裂重组蛋白家族REC8抗体
hz-7727R SMC2 染色体结构维持蛋白2抗体
hz-7728R SMC4 染色体结构维持蛋白4抗体
hz-7729R SMC5 染色体结构维持蛋白5抗体
hz-7730R SMC6 染色体结构维持蛋白6抗体
hz-7731R TRIP1/PSMC5 甲状腺受体相互作用蛋白1抗体
hz-7732R Separase 纺锤体级以外蛋白样1抗体
hz-7733R WAPL EBV核蛋白2抗体