产品详情
芳香烃受体抗体产品类别
兔抗人、大、小鼠AHR抗体
克 隆 号
浓缩液(1mg/1ml) 亲和纯化抗体
产品标准
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500
产品应用
(石蜡切片需做抗原修复)
芳香烃受体抗体产品介绍
Chromatin and Nuclear Signaling (染色质和核信号)
Unlike the steroid/thyroid hormone receptors, there is no known physiological ligand for the AH Receptor. Studies indicate that in non-ligand activated cells, AHR is found complexed with HSP90 predominantly in the cytoplasm. Upon binding to an agonist, the ligand-activated AHR is believed to transform to a nuclear, DNA binding form. This transformation process appears to involve dissociation of HSP90 from AHR followed by formation of a heterodimer with AHR nuclear translocator protein (Arnt). The AHR-ligand complex appears to initiate gene transcription of cytochrome P450 1A1.
[SUBCELLULAR LOCATION] Cytoplasm. Nucleus. Note=Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus.
[TISSUE SPECIFICITY] Expressed in all tissues tested including brain, heart, kidney, liver, lung, muscle, ovary, skin, spleen and thymus.
mol wt:93kDa
Other Aliases:
aryl hydrocarbon receptor; Ah receptor; Aromatic hydrocarbon receptor; Aryl hydrocarbon receptor; Aryl hydrocarbon receptor precursor;BHLHE76; Class E basic helix loop helix protein 76; HGNC:348.
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hz-1201P PAX8(Paired box gene 8) 配对盒基因8抗原
hz-1102P PAX9(Paired box gene 9) 配对盒基因9抗原
hz-1159P P-cadherin(placental) P-钙粘附分子抗原
hz-1617P LI-cadherin(liver-intestine cadherin) 肝肠钙粘连蛋白抗原
hz-1608P PDCD4(programmed cell death 4) 凋亡相关蛋白4抗原
hz-1333P TFAR19(TF-1 cell apoptsis-related gene 19) 凋亡相关蛋白TFAR19抗原
hz-2215P PCNA(phosphos Dyr211)peptide 磷酸化增殖细胞核多肽抗原
hz-1345P PCX/PODXL(Podocalyxin) 足细胞特异蛋白抗原
hz-1316P PDGF-BB peptide 血小板源性生长因子-BB抗原
hz-0923P Pdx1(pancreatic and duodenal homeobox 1) 胰十二指肠同源异型盒基因抗原
hz-2219P pectinesterase inhibitor 18 peptide 果胶酶抗原
hz-1084P PEG10(Paternally expressed gene 10) 肝癌高表达基因抗原
hz-2106P PENK/Enkephalin A(Preproencephalin A) 脑啡肽
hz-0584P PEPT2 (Peptide-transporters 2) 肠道肽转运蛋白2/小肽转运蛋白2抗原
hz-2469P PERK(PRKR-like endoplasmic reticulum kinase) 蛋白激酶R样内质网激酶抗原
hz-0796P FSCN1 (Fascin 1 protein; fascin homolog 1, actin-bundling protein) 纤维束蛋白同源物1/肌动蛋白集束蛋白/圆线虫紫癜 抗原
hz-0563P P-GP(P-glycoprotein) P-糖蛋白抗原
hz-1551P Pepsinogen C peptide 胃蛋白酶原C蛋白抗原
hz-1832P PGC-1 Alpha(peroxisome proliferator-activated receptor- Gamma coactivator 1 Alpha) 过氧化物酶体增殖物激活受体γ辅激活子1α抗原
hz-0823P PGRN (progranulin) 颗粒蛋白前体抗原
hz-1449P PHB(Prohibitin) 抑制素/肿瘤抑制因子抗原
hz-0520P PKA(Protein Kinase A) 蛋白激酶A(多肽)
hz-1098P PLAU/uPA (Plasminogen activator,urokinase) 尿激酶型纤溶酶原激活因子(多肽)
hz-1048P Podoplanin Protein 平足蛋白抗原
hz-0891P Pokhzon (POK Erythroid Myeloid Ontogenic factor) “扑克蒙”蛋白又称“波克曼”蛋白
hz-2157P Polycystin 1(Polycystic Kidney Disease 1) 多囊肾蛋白1抗原
hz-2158P Polycystin 2(polycystic kidney disease 2) 多囊肾蛋白2抗体
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hz-1436P RKIP(Raf kinase inhibitor protein) Raf激酶抑制蛋白抗原
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hz-2147P pre-X protein(CT)[Hepatitis B virus C-Terminus] 乙肝病毒pre-X蛋白抗原(C端)
hz-0532P PHD3 (Egln3; HIF-prolyl hydroxylase 3) 脯氨酸羟化酶(多肽)
hz-0433P ADAMTS-7(a disintegrin-like and metalloprotease-7 ) 新型金属基质蛋白酶(抗原)
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