磷酸化三磷酸腺柠檬酸裂解酶抗体Quantity size:

0.1ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and 磷酸化三磷酸腺柠檬酸裂解酶抗体oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

磷酸化三磷酸腺柠檬酸裂解酶抗体Also known as:

ATP citrate lyase (phospho S455); ACL; ATP citrate (pro-S) lyase; ATP citrate synthase; Citrate cleavage enzyme; EC 2.3.3.8; A730098H14RIK; ACLY; ATP CITRATE LYASE; ATPCL; AW538652; Cce; CITRATE LYASE;磷酸化三磷酸腺柠檬酸裂解酶抗体 CLATP; MGC124629; ACL; Acly; ACLY_HUMAN; ATP citrate lyase; ATP-citrate (pro-S-)-lyase; ATP-citrate synthase; ATPcitrate synthase; OTTHUMP00000164773.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, .

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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human ATP citrate lyase around the phosphorylation site of Ser455.

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Predicted Molecular Weight: 122kDa.

磷酸化三磷酸腺柠檬酸裂解酶抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:20-200  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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