Bloom综合征相关蛋白抗体Quantity size:

0.2ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Bloom’s syndrome is an autosomal recessive disorder characterized by pre- and post-natal growth deficiencies, sun sensitivity, immunodeficiency and a predisposition to various cancers. The gene responsible for Bloom’s syndrome, BLM, encodes a protein homologous to the RecQ helicase of E. coli and is mutated in most Bloom’s syndrome patients. One characteristic of Bloom’Bloom综合征相关蛋白抗体s syndrome is an increased frequency of sister chromatid exchange (SCE). BLM has been shown to unwind G4 DNA, and a failure of this function is thought to be responsible for the increased rate of SCE. BLM is known to be translocated to the nucleus, where its ATPase activity is stimulated by both single- and double-stranded DNA. Mutations in the yeast SGS1, a homolog of BLM, are known to cause mitotic hyperrecombination similiar to that observed in Bloom’s cells.

Bloom综合征相关蛋白抗体Also known as:

Blooms Syndrome Protein Blm; BLM; BLM_HUMAN; Bloom Syndrome; Bloom syndrome protein; Bloom syndrome RecQ helicase like; BS; DNA Helicase; DNA helicase RecQ like type 2; MGC126616; MGC131618; MGC131620; RECQ 2; RECQ like; RecQ like type 2; RecQ protein like 3; RecQ Protein-like 3; RECQ-2; RECQ-Like;Bloom综合征相关蛋白抗体 RecQ-like type 2; RECQ2; RECQL 2; RECQL 3; RECQL-2; RECQL-3; RECQL2; RECQL3; type 2.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human BLM/Blooms Syndrome Protein Blm.

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Bloom综合征相关蛋白抗体Predicted Molecular Weight: 159kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 

kl518Hu01铁蛋白(FE)多克隆抗体Polyclonal Antibody to Ferritin (FE)

kl518Mu01铁蛋白(FE)多克隆抗体Polyclonal Antibody to Ferritin (FE)

kl518Ra01铁蛋白(FE)多克隆抗体Polyclonal Antibody to Ferritin (FE)

kl355Hu01甲状腺球蛋白(TG)多克隆抗体Polyclonal Antibody to Thyroglobulin (TG)

kl355Mu01甲状腺球蛋白(TG)多克隆抗体Polyclonal Antibody to Thyroglobulin (TG)

kl355Ra01甲状腺球蛋白(TG)多克隆抗体Polyclonal Antibody to Thyroglobulin (TG)

kl821Mu01C反应蛋白(CRP)多克隆抗体Polyclonal Antibody to C Reactive Protein (CRP)

kl821Ra01C反应蛋白(CRP)多克隆抗体Polyclonal Antibody to C Reactive Protein (CRP)

kl216Hu01绒毛膜促性腺激素(CG)多克隆抗体Polyclonal Antibody to Chorionic Gonadotropin (CG)

kl930Hu01脱铁转铁蛋白(apoTf)多克隆抗体Polyclonal Antibody to Apotransferrin (apoTf)

kl037Hu01纤连蛋白(FN)多克隆抗体Polyclonal Antibody to Fibronectin (FN)

kl037Mu01纤连蛋白(FN)多克隆抗体Polyclonal Antibody to Fibronectin (FN)

kl037Ra01纤连蛋白(FN)多克隆抗体Polyclonal Antibody to Fibronectin (FN)

kl082Hu01层粘连蛋白(LN)多克隆抗体Polyclonal Antibody to Laminin (LN)

kl082Ra01层粘连蛋白(LN)多克隆抗体Polyclonal Antibody to Laminin (LN)

kl184Hu01粘蛋白21(MUC21)多克隆抗体Polyclonal Antibody to Mucin 21 (MUC21)

kl995Hu01粘蛋白20(MUC20)多克隆抗体Polyclonal Antibody to Mucin 20 (MUC20)

kl995Mu01粘蛋白20(MUC20)多克隆抗体Polyclonal Antibody to Mucin 20 (MUC20)

kl995Ra01粘蛋白20(MUC20)多克隆抗体Polyclonal Antibody to Mucin 20 (MUC20)

kl995Bo01粘蛋白20(MUC20)多克隆抗体Polyclonal Antibody to Mucin 20 (MUC20)

Optimal working dilutions must be determined by the end user.