?磷酸化酪氨酸蛋白激酶6/乳腺肿瘤激酶抗体Quantity size:

0.1ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

This protein encoded is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype.磷酸化酪氨酸蛋白激酶6/乳腺肿瘤激酶抗体 Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. Its presence in the nucleus appears to be linked to suppression of tumor progression. The encoded protein has been shown to undergo autophosphorylation.

Also known as:

Brk (phospho Y447); p-Brk 磷酸化酪氨酸蛋白激酶6/乳腺肿瘤激酶抗体(phospho Y447); Breast tumor kinase; Breast tumour kinase; Protein tyrosine kinase 6; PTK6; Tyrosine protein kinase BRK; PTK6_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, .

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Immunogen: KLH conjugated 磷酸化酪氨酸蛋白激酶6/乳腺肿瘤激酶抗体synthesised phosphopeptide derived from human Brk around the phosphorylation site of Tyr447 [TS(p-Y)EN].

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Predicted Molecular Weight: 52kDa.

Storage:

磷酸化酪氨酸蛋白激酶6/乳腺肿瘤激酶抗体Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:10-100  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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