剪切和多聚腺苷酸化特异性因子4抗体Quantity size:

0.2ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs.剪切和多聚腺苷酸化特异性因子4抗体 In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene.剪切和多聚腺苷酸化特异性因子4抗体 [provided by RefSeq, Jul 2008]

Also known as:

Cleavage and polyadenylation specificity factor 30 kDa subunit; CPSF 30 kDa subunit; CPSF30; CPSF4; NAR; NEB1; No arches homolog; NS1 effector domain binding protein 1; CPSF4_RAT.

Specificity:

●

Rabbit Polyclonal IgG,剪切和多聚腺苷酸化特异性因子4抗体 affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, .

●

Immunogen: KLH conjugated synthetic peptide derived from human CPSF4/CPSF30.

●

剪切和多聚腺苷酸化特异性因子4抗体Predicted Molecular Weight: 27kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl400Ra01视黄醇结合蛋白1(RBP1)多克隆抗体Polyclonal Antibody to Retinol Binding Protein 1, Cellular (RBP1)

kl372Hu01凝溶胶蛋白(GS)多克隆抗体Polyclonal Antibody to Gelsolin (GS)

kl372Mu01凝溶胶蛋白(GS)多克隆抗体Polyclonal Antibody to Gelsolin (GS)

kl372Ra01凝溶胶蛋白(GS)多克隆抗体Polyclonal Antibody to Gelsolin (GS)

kl217Hu01α1-微球蛋白(α1M)多克隆抗体Polyclonal Antibody to Alpha-1-Microglobulin/Bikunin Precursor (a1M)

kl217Mu01α1-微球蛋白(α1M)多克隆抗体Polyclonal Antibody to Alpha-1-Microglobulin/Bikunin Precursor (a1M)

kl217Ra01α1-微球蛋白(α1M)多克隆抗体Polyclonal Antibody to Alpha-1-Microglobulin/Bikunin Precursor (a1M)

kl050Mu01胰岛素样生长因子1(IGF1)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor 1 (IGF1)

kl050Ra01胰岛素样生长因子1(IGF1)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor 1 (IGF1)

kl864Hu01乳酸脱氢酶(LDH)多克隆抗体Polyclonal Antibody to Lactate Dehydrogenase (LDH)

kl864Mu01乳酸脱氢酶(LDH)多克隆抗体Polyclonal Antibody to Lactate Dehydrogenase (LDH)

kl864Ra01乳酸脱氢酶(LDH)多克隆抗体Polyclonal Antibody to Lactate Dehydrogenase (LDH)

kl864Bo01乳酸脱氢酶(LDH)多克隆抗体Polyclonal Antibody to Lactate Dehydrogenase (LDH)

kl864Po01乳酸脱氢酶(LDH)多克隆抗体Polyclonal Antibody to Lactate Dehydrogenase (LDH)

kl560Hu01表皮生长因子(EGF)多克隆抗体Polyclonal Antibody to Epidermal Growth Factor (EGF)

kl560Mu01表皮生长因子(EGF)多克隆抗体Polyclonal Antibody to Epidermal Growth Factor (EGF)

kl560Ra01表皮生长因子(EGF)多克隆抗体Polyclonal Antibody to Epidermal Growth Factor (EGF)

kl543Hu01免疫球蛋白M(IgM)多克隆抗体Polyclonal Antibody to Immunoglobulin M (IgM)

kl543Mu01免疫球蛋白M(IgM)多克隆抗体Polyclonal Antibody to Immunoglobulin M (IgM)

kl543Ra01免疫球蛋白M(IgM)多克隆抗体Polyclonal Antibody to Immunoglobulin M (IgM)

kl543Bo01免疫球蛋白M(IgM)多克隆抗体Polyclonal Antibody to Immunoglobulin M (IgM)

kl543Cp01免疫球蛋白M(IgM)多克隆抗体Polyclonal Antibody to Immunoglobulin M (IgM)

kl543Ga01免疫球蛋白M(IgM)多克隆抗体Polyclonal Antibody to Immunoglobulin M (IgM)

kl544Hu01免疫球蛋白G(IgG)多克隆抗体Polyclonal Antibody to Immunoglobulin G (IgG)

kl544Mu01免疫球蛋白G(IgG)多克隆抗体Polyclonal Antibody to Immunoglobulin G (IgG)