Quantity size:

0.2ml

Concentration:

1mg/ml 信号转导蛋白亚基6抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. 信号转导蛋白亚基6抗体The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Has some glucocorticoid receptor-responsive activity.

信号转导蛋白亚基6抗体Also known as:

JAB1 containing signalosome subunit 6; COP9 subunit 6 (MOV34 homolog, 34 kD); MOV34 homolog, 34 kD; COP9 (constitutive photomorphogenic), subunit 6; COP9 complex S6; COP9 signalosome complex subunit 6; COP9 signalosome subunit 6; cops6; CSN6; CSN6_HUMAN; hVIP; JAB1-containing signalosome subunit 6;信号转导蛋白亚基6抗体 MOV34 homolog; MOV34-34KD; Sgn3; SGN6; Signalosome subunit 6; VIP/MOV34; Vpr interacting protein; Vpr-interacting protein.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, .

●

Immunogen: KLH conjugated synthetic peptide derived from human COPS6.

●

信号转导蛋白亚基6抗体Predicted Molecular Weight: 36kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:50-200   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl106Hu01骨成型蛋白10(BMP10)多克隆抗体Polyclonal Antibody to Bone Morphogenetic Protein 10 (BMP10)

kl106Mu01骨成型蛋白10(BMP10)多克隆抗体Polyclonal Antibody to Bone Morphogenetic Protein 10 (BMP10)

kl107Hu01骨形成蛋白15(BMP15)多克隆抗体Polyclonal Antibody to Bone Morphogenetic Protein 15 (BMP15)

kl108Hu01生长分化因子1(GDF1)多克隆抗体Polyclonal Antibody to Growth Differentiation Factor 1 (GDF1)

kl109Mu01生长分化因子3(GDF3)多克隆抗体Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3)

kl109Ra01生长分化因子3(GDF3)多克隆抗体Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3)

kl110Hu01生长分化因子5(GDF5)多克隆抗体Polyclonal Antibody to Growth Differentiation Factor 5 (GDF5)

kl113Mu01生长分化因子11(GDF11)多克隆抗体Polyclonal Antibody to Growth Differentiation Factor 11 (GDF11)

kl123Hu01Smad同源物3(Smad3)多克隆抗体Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3)

kl123Ra01Smad同源物3(Smad3)多克隆抗体Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3)

kl124Mu01Smad同源物2(Smad2)多克隆抗体Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 2 (Smad2)

kl125Hu01Cerberus蛋白(CER)多克隆抗体Polyclonal Antibody to Cerberus (CER)

kl126Ra01腱蛋白(CHRD)多克隆抗体Polyclonal Antibody to Chordin (CHRD)

kl127Hu01核心蛋白聚糖(DCN)多克隆抗体Polyclonal Antibody to Decorin (DCN)

kl128Hu01Gremlin 1蛋白(GREM1)多克隆抗体Polyclonal Antibody to Gremlin 1 (GREM1)

kl128Mu01Gremlin 1蛋白(GREM1)多克隆抗体Polyclonal Antibody to Gremlin 1 (GREM1)

kl130Hu01头蛋白(NOG)多克隆抗体Polyclonal Antibody to Noggin (NOG)

kl130Mu01头蛋白(NOG)多克隆抗体Polyclonal Antibody to Noggin (NOG)

kl130Ra01头蛋白(NOG)多克隆抗体Polyclonal Antibody to Noggin (NOG)