产品详情
Quantity size:
0.2ml
Concentration:
1mg/ml 脊髓灰质炎受体相关蛋白1抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Nectin is a Ca2+-independent homophilic cell adhesion molecule that belongs to the immunoglobulin superfamily. Human Nectin is identical to the poliovirus receptor-related protein (PRR) and is identified to be the alphaherpesvirus entry mediator. Nectin constitutes a family consisting of at least nectin 1, 2 and 3. Nectin 2 and 3 are ubiquitously expressed,脊髓灰质炎受体相关蛋白1抗体 whereas nectin 1 is abundantly expressed in the brain. Nectin 1 exists as nectin 1? and 1∫/HIgR, produced by alternative splicing. The cytoplasmic regions of Nectin 1?, but not Nectin 1∫/HIgR, have a C-terminal conserved motif (E/A-X-Y-V). This motif interacts with the PDZ domain of the F-Actin-binding protein, afadin, through which it is linked to the Actin cytoskeleton. Nectin 1, also designated HveC/ PRR1, allows the entry 脊髓灰质炎受体相关蛋白1抗体 of herpes simplex virus type 1 (HSV-1) and HSV-2 into mammalian cells. The interaction of virus envelope glycoprotein D (gD) with nectin 1 is an essential step in the process leading to membrane fusion; the gD binding site is located at the first Ig-like domain of Nectin 1. Both the transinteraction of nectin and the interaction of nectin with afadin are necessary for their co-localization with E-cadherin and catenins at adherens junctions.
Also known as:
CD111; CD111 antigen; CLPED1; ectodermal dysplasia 4 (Margarita Island type); ED4; Herpes virus entry mediator C; Herpesvirus entry mediator C; Herpesvirus Ig like receptor; Herpesvirus Ig-like receptor; HIgR; HveC; Nectin 1; Nectin-1; Nectin1; OFC7; OROFACIAL CLEFT 7;脊髓灰质炎受体相关蛋白1抗体 Poliovirus receptor related protein 1; poliovirus receptor-like 1; Poliovirus receptor-related protein 1; PRR; PRR1; PVRL 1; PVRL1; PVRL1_HUMAN; PVRR; PVRR1; SK-12.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Cow, Rabbit, .
●
Immunogen: KLH conjugated synthetic peptide derived from human PVRL1/CD111/Nectin1.
●
脊髓灰质炎受体相关蛋白1抗体 Predicted Molecular Weight: 54kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl156Hu01Ⅹ型胶原(COL10)多克隆抗体Polyclonal Antibody to Collagen Type X (COL10)
kl156Mu01Ⅹ型胶原(COL10)多克隆抗体Polyclonal Antibody to Collagen Type X (COL10)
kl156Ra01Ⅹ型胶原(COL10)多克隆抗体Polyclonal Antibody to Collagen Type X (COL10)
kl157Hu01Ⅺ型胶原α1(COL11α1)多克隆抗体Polyclonal Antibody to Collagen Type XI Alpha 1 (COL11a1)
kl158Hu01Ⅻ型胶原(COL12)多克隆抗体Polyclonal Antibody to Collagen Type XII (COL12)
kl158Mu01Ⅻ型胶原(COL12)多克隆抗体Polyclonal Antibody to Collagen Type XII (COL12)
kl169Hu01神经秩蛋白(NRTN)多克隆抗体Polyclonal Antibody to Neurturin (NRTN)
kl170Hu01Persephin蛋白(PSPN)多克隆抗体Polyclonal Antibody to Persephin (PSPN)
kl170Mu01Persephin蛋白(PSPN)多克隆抗体Polyclonal Antibody to Persephin (PSPN)
kl172Hu01神经调节素2(NRG2)多克隆抗体Polyclonal Antibody to Neuregulin 2 (NRG2)
kl173Hu01神经调节素3(NRG3)多克隆抗体Polyclonal Antibody to Neuregulin 3 (NRG3)
kl174Hu01神经调节素4(NRG4)多克隆抗体Polyclonal Antibody to Neuregulin 4 (NRG4)
kl175Hu01左右决定因子1(LEFTY1)多克隆抗体Polyclonal Antibody to Left/Right Determination Factor 1 (LEFTY1)
kl176Hu01多聚A特异性核糖核酸酶(klN)多克隆抗体Polyclonal Antibody to Poly A Specific Ribonuclease (klN)
kl177Hu01短蛋白聚糖(BCAN)多克隆抗体Polyclonal Antibody to Brevican (BCAN)
kl186Hu01肝细胞生长因子受体(HGFR)多克隆抗体Polyclonal Antibody to Heklocyte Growth Factor Receptor (HGFR)
kl192Hu01Axis抑制蛋白2(AXIN2)多克隆抗体Polyclonal Antibody to Axis Inhibition Protein 2 (AXIN2)
kl195Hu01分拣连接蛋白13(SNX13)多克隆抗体Polyclonal Antibody to Sorting Nexin 13 (SNX13)
kl196Hu01连接桥粒斑珠蛋白(JUP)多克隆抗体Polyclonal Antibody to Junction Plakoglobin (JUP)
kl200Ra01早老素1(PSEN1)多克隆抗体Polyclonal Antibody to Presenilin 1 (PSEN1)
kl202Hu01桥粒芯糖蛋白2(DSG2)多克隆抗体Polyclonal Antibody to Desmoglein 2 (DSG2)