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上海康朗生物科技有限公司
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Quantity size:

0.2ml

Concentration:

1mg/ml 诱捕受体2抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L, a member of the TNF family, induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are functional receptors for TRAIL,诱捕受体2抗体 and DcR1/TRID is a decoy receptor. Another member of the TRAIL receptor family was identified and designated DcR2. The DcR2 receptor is 386 amino acids in length and has an extracellular TRAIL binding domain, but lacks intracellular death domain and does not induce apoptosis. Although this receptor binds to the cytotoxic ligand TRAIL, it contains a truncated death domain and functions as an inhibitory receptor. When overexpressed, the DcR2 receptor can protect cells against TRAIL mediated cytotoxicity. Like DR4 and DR5, DcR2 transcript is widely expressed in a variety of normal human tissues but DcR2 is absent in most tumors. Ultraviolet radiation has been shown to upregulate DcR2 expression on human keratinocytes. Over expression of DcR2 attenuated TRAIL induced apoptosis.

诱捕受体2抗体Also known as:

TNFRSF10D; Decoy receptor 2; CD 264; CD264; CD-264; DcR 2; decoy with truncated death domain; ID; TNF receptor related receptor for TRAIL; TNF related apoptosis inducing ligand receptor 4; TNFRSF 10D; TRAIL R4; TRAIL receptor 4; TRAIL receptor with a truncated death domain; TRAILR4; TRIALR 4;诱捕受体2抗体 TRUNDD; Tumor necrosis factor receptor superfamily member 10d decoy with truncated death domain; Tumor necrosis factor receptor superfamily member 10D precursor; TR10D_HUMAN.

Specificity:

Rabbit Polyclonal IgG, affinity purified by Protein A.

Reacts with: Human, .

Immunogen: KLH conjugated synthetic peptide derived from human DcR2.

诱捕受体2抗体Predicted Molecular Weight: 36kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:20-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl251Hu01肿瘤坏死因子配体超家族成员7(TNFSF7)多克隆抗体Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)

kl252Hu01雄激素受体(AR)多克隆抗体Polyclonal Antibody to Androgen Receptor (AR)

kl252Mu01雄激素受体(AR)多克隆抗体Polyclonal Antibody to Androgen Receptor (AR)

kl252Ra01雄激素受体(AR)多克隆抗体Polyclonal Antibody to Androgen Receptor (AR)

kl253Ra01脯氨酰羧肽酶(PRCP)多克隆抗体Polyclonal Antibody to Prolylcarboxypeptidase (PRCP)

kl256Hu01基质金属蛋白酶26(MMP26)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 26 (MMP26)

kl258Hu01谷氨酸脱羧酶2(GAD2)多克隆抗体Polyclonal Antibody to Glutamate Decarboxylase 2, Acid (GAD2)

kl258Ra01谷氨酸脱羧酶2(GAD2)多克隆抗体Polyclonal Antibody to Glutamate Decarboxylase 2, Acid (GAD2)

kl261Hu01CD72分子(CD72)多克隆抗体Polyclonal Antibody to Cluster Of Differentiation 72 (CD72)

kl262Hu01整合素β3(ITGβ3)多克隆抗体Polyclonal Antibody to Integrin Beta 3 (ITGb3)

kl263Mu01精氨酸加压素受体1B(AVPR1B)多克隆抗体Polyclonal Antibody to Arginine Vasopressin Receptor 1B (AVPR1B)

kl265Hu01胰多肽(PP)多克隆抗体Polyclonal Antibody to klcreatic Polypeptide (PP)

kl265Mu01胰多肽(PP)多克隆抗体Polyclonal Antibody to klcreatic Polypeptide (PP)

kl266Ga01胰高血糖素(GC)多克隆抗体Polyclonal Antibody to Glucagon (GC)

kl267Hu01激肽原1(KNG1)多克隆抗体Polyclonal Antibody to Kininogen 1 (KNG1)

kl267Mu01激肽原1(KNG1)多克隆抗体Polyclonal Antibody to Kininogen 1 (KNG1)

kl267Ra01激肽原1(KNG1)多克隆抗体Polyclonal Antibody to Kininogen 1 (KNG1)

kl268Hu01苯酚磺基转移酶(PST)多克隆抗体Polyclonal Antibody to Phenol Sulfotransferase (PST)

kl268Mu01苯酚磺基转移酶(PST)多克隆抗体Polyclonal Antibody to Phenol Sulfotransferase (PST)