Quantity size:

0.2ml

Concentration:

1mg/ml  吞噬细胞运动蛋白2抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Elmo (engulfment and cell motility) proteins share similarity to C. elegans CED-12. The C. elegans genes ced-2, ced-5, ced-10, and ced-12 and their mammalian homologs CRKII, DOCK1, RAC1 and ELMO mediate cytoskeletal rearrangements during phagocytosis of apoptotic cells and cell motility. Elmo1 associates with DOCK 180 and may influence phagocytosis and effect cell shape changes. Src family kinase mediated tyrosine phosphorylation 吞噬细胞运动蛋白2抗体of ELMO1 influences signaling through Elmo1/Crk/DOCK 180 pathways. Elmo2 interacts directly with Rho G in a GTP-dependent manner and forms a ternary complex with DOCK 180 to induce activation of Rac 1. The RhoG-Elmo2-DOCK 180 pathway is required for activation of Rac 1 and cell spreading mediated by integrin, as well as for neurite outgrowth induced by nerve growth factor. Elmo3 acts in assocation with DOCK180 and Crk II and may be required in complex with DOCK180 to activate Rac/Rho small GTPases.

吞噬细胞运动蛋白2抗体Also known as:

CED 12; Ced 12 homolog 2; CED 12 homolog A; CED 12A; CED-12; ced-12 homolog 2; CED12; CED12 homolog A; CED12A; ELMO 2; ELMO-2; ELMO2; ELMO2_HUMAN; Engulfment and cell motility 2 (ced 12 homolog, C. elegans); Engulfment and cell motility 2; Engulfment and cell motility protein 2;吞噬细胞运动蛋白2抗体 FLJ11656; hCED 12A; hCED-12A; hCED12A; KIAA1834; PH domain protein CED12A; Protein ced 12 homolog A; Protein ced-12 homolog A.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, .

●

Immunogen: KLH conjugated synthetic peptide derived from human ELMO2.

●

Predicted Molecular Weight: 83kDa.

吞噬细胞运动蛋白2抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl504Ra01肿瘤坏死因子受体超家族成员1B(TNFRSF1B)多克隆抗体Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B)

kl505Hu01白介素3受体α(IL3Rα)多克隆抗体Polyclonal Antibody to Interleukin 3 Receptor Alpha (IL3Ra)

kl510Hu01白介素5受体α(IL5Rα)多克隆抗体Polyclonal Antibody to Interleukin 5 Receptor Alpha (IL5Ra)

kl510Mu01白介素5受体α(IL5Rα)多克隆抗体Polyclonal Antibody to Interleukin 5 Receptor Alpha (IL5Ra)

kl513Hu01烟碱型胆碱受体β2(CHRNβ2)多克隆抗体Polyclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 2 (CHRNb2)

kl514Hu01白介素1受体关联激酶1(IRAK1)多克隆抗体Polyclonal Antibody to Interleukin 1 Receptor Associated Kinase 1 (IRAK1)

kl516Hu01凸素1(PROM1)多克隆抗体Polyclonal Antibody to Prominin 1 (PROM1)

kl517Hu01颗粒溶素(GNLY)多克隆抗体Polyclonal Antibody to Granulysin (GNLY)

kl518Hu01白介素1受体关联激酶4(IRAK4)多克隆抗体Polyclonal Antibody to Interleukin 1 Receptor Associated Kinase 4 (IRAK4)

kl520Hu01白介素1受体关联激酶3(IRAK3)多克隆抗体Polyclonal Antibody to Interleukin 1 Receptor Associated Kinase 3 (IRAK3)

kl521Hu01黏膜地址素细胞黏附分子(MAdCAM1)多克隆抗体Polyclonal Antibody to Mucosal Addressin Cell Adhesion Molecule 1 (MAdCAM1)

kl522Hu01肺部激活调节趋化因子(klC)多克隆抗体Polyclonal Antibody to Pulmonary Activation Regulated Chemokine (klC)

kl523Mu01趋化因子C-X3-C-基元受体1(CX3CR1)多克隆抗体Polyclonal Antibody to Chemokine C-X3-C-Motif Receptor 1 (CX3CR1)

kl524Hu01神经元凋亡抑制蛋白(NAIP)多克隆抗体Polyclonal Antibody to Neuronal Apoptosis Inhibitory Protein (NAIP)

kl530Hu01血小板膜糖蛋白Ⅳ(GP4)多克隆抗体Polyclonal Antibody to Platelet Membrane Glycoprotein IV (GP4)

kl532Hu01维甲酸诱导基因1蛋白(RIG1)多克隆抗体Polyclonal Antibody to Retinoic Acid Inducible Gene 1 Protein (RIG1)

kl533Hu01基质金属蛋白酶16(MMP16)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 16 (MMP16)

kl537Hu01丝氨酸蛋白酶2(PRSS2)多克隆抗体Polyclonal Antibody to Protease, Serine 2 (PRSS2)

kl538Hu01细胞胱硫醚γ裂解酶(CSE)多克隆抗体Polyclonal Antibody to Cystathionine Gamma Lyase (CSE)

kl538Ra01细胞胱硫醚γ裂解酶(CSE)多克隆抗体Polyclonal Antibody to Cystathionine Gamma Lyase (CSE)

kl539Hu01血清淀粉样P物质(SAP)多克隆抗体Polyclonal Antibody to Serum Amyloid P Component (SAP)

kl539Mu01血清淀粉样P物质(SAP)多克隆抗体Polyclonal Antibody to Serum Amyloid P Component (SAP)

kl539Ra01血清淀粉样P物质(SAP)多克隆抗体Polyclonal Antibody to Serum Amyloid P Component (SAP)

kl540Hu01细胞外基质金属蛋白酶诱导因子(EMMPRIN)多克隆抗体Polyclonal Antibody to Extracellular Matrix Metalloproteinase Inducer (EMMPRIN)

kl542Hu01甘露糖受体C1(MRC1)多克隆抗体Polyclonal Antibody to Mannose Receptor C Type 1 (MRC1)