产品详情
Quantity size:
0.1ml
Concentration:
1mg/ml 磷酸化有丝分裂驱动蛋白样2抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell (1-3). Individual kinesin members play crucial roles in cell division, intracellular transport, and membrane trafficking events including endocytosis and transcytosis (3,4). KIF1C is a member of the KIF1/Unc104 family of kinesin-like 磷酸化有丝分裂驱动蛋白样2抗体proteins, which are involved in the transport of mitochondria or synaptic vesicles in axons (5). Human KIF1C maps to chromosome 17p13 and encodes a predicted 1,103 amino acid protein with abundant expression in heart and skeletal muscle (5). Tyrosine phosphorylation is a putative regulator of KIF1C mediated retrograde transport of Golgi vesicles 磷酸化有丝分裂驱动蛋白样2抗体to the endoplasmic reticulum (5). KIF1C is capable of forming homodimers and can noncovalently associate with 14-3-3 beta, gamma, epsilon and zeta (6). In mouse macrophages, KIF1C is required for anthrax lethal toxin resistance (7).
Also known as:
KIF20A (phospho S528); p-KIF20A (phospho S528); GG10 2; GG10_2; Kif20a; kinesin family member 20A; Kinesin like protein KIF20A; Kinesin-like protein 174; mitotic kinesin like protein 2; MKLP2; RAB6 interacting, kinesin like (rabkinesin6); Rab6-interacting kinesin-like protein;磷酸化有丝分裂驱动蛋白样2抗体 RAB6-INTERACTING PROTEIN, KINESIN-LIKE; RAB6KIFL; Rabkinesin 6; AA415432; FLJ21151.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Rat, .
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Immunogen: KLH conjugated synthesised phosphopeptide derived from human.
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Predicted Molecular Weight: 100kDa.
磷酸化有丝分裂驱动蛋白样2抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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