产品详情
Quantity size:
0.2ml
Concentration:
1mg/ml 自噬微管相关蛋白轻链β3抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and in maintaining the balance between neuronal plasticity and rigidity. MAP-light chain 3 beta (MAP-LC3 Beta) and MAP-light chain 3 alpha (MAP-LC3 alpha) are subunits of both MAP1A and MAP1B. MAP-LC3M Beta, a homolog of Apg8p, is essential for autophagy and associated to the autophagosome membranes after processing. Two forms of LC3 Beta, the cytosolic LC3-I and the membrane-bound LC3-II, are produced post-translationally. LC3-I is formed by the removal of the C-terminal自噬微管相关蛋白轻链β3抗体 22 amino acids from newly synthesized LC3∫, followed by the conversion of a fraction of LC3-I into LC3-II. LC3 enhances fibronectin mRNA translation in ductus arteriosus cells through association with 60S ribosomes and binding to an AU-rich element in the 3’ untranslated region of fibronectin mRNA. This facilitates sorting of fibronectin mRNA onto rough endoplasmic reticulum and translation. MAP LC3 Beta may also be involved in formation of autophagosomal vacuoles. It is expressed primarily in heart, testis, brain and skeletal muscle.
VAlso known as:
自噬微管相关蛋白轻链β3抗体Microtubule-associated proteins 1B light chain 3A; Microtubule-associated proteins 1Beta light chain 3A; MAP1B LC3 A; MAP LC3 Beta; MAP-LC3 Beta; MAP1 light chain 3-like protein 1; MAP1LC3A; MLP3A_HUMAN; Microtubule-associated proteins 1A/1B light chain 3A; Autophagy-related protein LC3 A; Autophagy-related ubiquitin-like modifier LC3 A; MAP1 light chain 3-like protein 1; MAP1A/MAP1B light chain 3 A; MAP1A/MAP1B LC3 A; Microtubule-associated protein 1 light chain 3 alpha.
Specificity:
●
Rabbit Polyclonal IgG,自噬微管相关蛋白轻链β3抗体 affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, .
●
Immunogen: KLH conjugated synthetic peptide derived from human Microtubule-associated proteins 1A/1B light chain 3A.
●
Predicted Molecular Weight: 14kDa.
自噬微管相关蛋白轻链β3抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl322Hu01基质金属蛋白酶15(MMP15)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15)
kl322Mu01基质金属蛋白酶15(MMP15)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15)
kl322Po01基质金属蛋白酶15(MMP15)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15)
kl323Hu01不均一核糖核蛋白A2/B1(HNRPA2B1)多克隆抗体Polyclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRPA2B1)
kl329Hu01多功能肽酶2(LMP2)多克隆抗体Polyclonal Antibody to Large Multifunctional Peptidase 2 (LMP2)
kl335Ra01尾加压素2受体(UTS2R)多克隆抗体Polyclonal Antibody to Urotensin 2 Receptor (UTS2R)
kl338Mu01微管关联蛋白1A(MAP1A)多克隆抗体Polyclonal Antibody to Microtubule Associated Protein 1A (MAP1A)
kl340Hu01蛛毒素受体3(LPHN3)多克隆抗体Polyclonal Antibody to Latrophilin 3 (LPHN3)
kl344Hu01回肠脂肪酸结合蛋白(FABP6)多克隆抗体Polyclonal Antibody to Fatty Acid Binding Protein 6, Ileal (FABP6)
kl344Mu01回肠脂肪酸结合蛋白(FABP6)多克隆抗体Polyclonal Antibody to Fatty Acid Binding Protein 6, Ileal (FABP6)
kl347Hu01着丝粒蛋白F(CENPF)多克隆抗体Polyclonal Antibody to Centromere Protein F (CENPF)
kl350Mu01Ⅰ型胶原α1(COL1α1)多克隆抗体Polyclonal Antibody to Collagen Type I Alpha 1 (COL1a1)
kl350Ra01Ⅰ型胶原α1(COL1α1)多克隆抗体Polyclonal Antibody to Collagen Type I Alpha 1 (COL1a1)
kl357Hu01成纤维细胞生长因子5(FGF5)多克隆抗体Polyclonal Antibody to Fibroblast Growth Factor 5 (FGF5)
kl362Hu01尾加压素2(UST2)多克隆抗体Polyclonal Antibody to Urotensin 2 (UST2)
kl363Hu01血小板内皮细胞粘附分子1(PECAM1)多克隆抗体Polyclonal Antibody to Platelet/Endothelial Cell Adhesion Molecule (PECAM1)
kl363Mu01血小板内皮细胞粘附分子1(PECAM1)多克隆抗体Polyclonal Antibody to Platelet/Endothelial Cell Adhesion Molecule (PECAM1)
kl363Ra01血小板内皮细胞粘附分子1(PECAM1)多克隆抗体Polyclonal Antibody to Platelet/Endothelial Cell Adhesion Molecule (PECAM1)
kl370Hu01β-血小板球蛋白(βTG)多克隆抗体Polyclonal Antibody to Beta-Thromboglobulin (bTG)
kl370Mu01β-血小板球蛋白(βTG)多克隆抗体Polyclonal Antibody to Beta-Thromboglobulin (bTG)
kl370Ra01β-血小板球蛋白(βTG)多克隆抗体Polyclonal Antibody to Beta-Thromboglobulin (bTG)
kl371Bo0110kDa干扰素γ诱导蛋白(IP10)多克隆抗体Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)
kl371Ca0110kDa干扰素γ诱导蛋白(IP10)多克隆抗体Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)
kl371Hu0110kDa干扰素γ诱导蛋白(IP10)多克隆抗体Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)
kl371Mu0110kDa干扰素γ诱导蛋白(IP10)多克隆抗体Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)
kl371Ra0110kDa干扰素γ诱导蛋白(IP10)多克隆抗体Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)
kl373Hu01结蛋白(Des)多克隆抗体Polyclonal Antibody to Desmin (Des)