产品详情
Quantity size:
0.2ml
Concentration:
1mg/ml 微小染色体维持缺陷蛋白10抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the 微小染色体维持缺陷蛋白10抗体recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
微小染色体维持缺陷蛋白10抗体Also known as:
FLJ31133 ; HsMCM10 ; mcm10 ; MCM10 minichromosome maintenance deficient 10 ; MCM10_HUMAN ; Minichromosome maintenance protein 10 isoform 1 ; PRO2249 ; Protein MCM10 homolog.
Specificity:
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Rabbit Polyclonal IgG, 微小染色体维持缺陷蛋白10抗体affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, Cat, .
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Immunogen: KLH conjugated synthetic peptide derived from human MCM10.
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Predicted Molecular Weight: 98kDa.
微小染色体维持缺陷蛋白10抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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