Quantity size:

0.2ml

Concentration:

1mg/ml  轴索过度生长抑制因子受体/Nogo受体抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Axons are essential for neuronal communication but they do not regenerate after injury to the adult mammalian brain or spinal cord. Failed regeneration is due in part to the production of a potent axonal growth inhibitor, Nogo, by myelinating cells. The finding of a high affinity轴索过度生长抑制因子受体/Nogo受体抗体 axonal receptor for the extracellular domain of Nogo provides the first insight into the basis of Nogo action. Disrupting the interaction of Nogo with the Nogo-66 receptor may facilitate axonal regeneration in vivo. The protein is dubbed the Nogo receptor because it binds with several other proteins that block neural growth. It is found to be ubiquitous in the brain and spinal cord.

轴索过度生长抑制因子受体/Nogo受体抗体Also known as:

NgR; Nogo-66 receptor; Nogor; NogoR; Nogo-R; Reticulon 4 receptor; Rtn4r; RTN4R_RAT.

Specificity:

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Rabbit Polyclonal IgG,轴索过度生长抑制因子受体/Nogo受体抗体 affinity purified by Protein A.

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Reacts with: Mouse, Rat, .

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Immunogen: KLH conjugated synthetic peptide derived from mouse Nogo R.

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Predicted Molecular Weight: 48kDa.

轴索过度生长抑制因子受体/Nogo受体抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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