Quantity size:

0.2ml

Concentration:

1mg/ml 孕激素受体膜相关元件抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

PGRMC1 is a progesterone receptor component of 195 aa with a 26 residue N terminal hydrophobic region and no N terminal glycosylation site. It has an overall homology of 50% with PGRMC2 but their C terminal regions have a 68% homology, including a highly conserved 58 residue 孕激素受体膜相关元件抗体sequence.PGRMC1 is a heme bind proteins that is up-regulated in several cancers. In breast tumors, PGRMC1 is associated with hypoxia estrogen receptor-negative status. PGRMC1 is also shown to stimulate AKT phosphorylation and is known to stabilise the EGFR receptor tyrosine kinase.

孕激素受体膜相关元件抗体Also known as:

HPR6.6; Membrane associated progesterone receptor component 1; y mPR; PGRMC1; PGRMC 1; PGRMC-1; Progesterone receptor membrane component 1.

Specificity:

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Rabbit Polyclonal IgG,孕激素受体膜相关元件抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human PGRMC (75-120aa).

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Predicted Molecular Weight: 21kDa.

Storage:

孕激素受体膜相关元件抗体Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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