Quantity size:

0.2ml

Concentration:

1mg/ml 胞粘蛋白结合调节蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

CYTIP is a cytoplasmic protein that is involved in lymphocytic cell adhesion. Expressed primarily in hematopoetic cells, CYTIP regulates the activity of cytohesin-1 (an integrin-activating protein involved in cell adhesion) by mediating its recruitment to the leukocyte membrane. Through its ability to bind cytohesin-1, CYTIP is able to sequester it 胞粘蛋白结合调节蛋白抗体to the cytoplasm, thereby preventing cytohesin-1 translocation to lymphocytes and interrupting the flow of information in the cell adhesion pathway. CYTIP can be recruited from the cytoplasm to the membrane by leukocyte integrins which interact with CYTIP through its PDZ domain. After membrane translocation, CYTIP can be re-located to the cytoplasm via exposure to a phorbol ester. Additionally, CYTIP associates with SNX27 (sorting nexin 27) and helps to 胞粘蛋白结合调节蛋白抗体coordinate trafficking and signaling complexes. Up-regulation of CYTIP is observed in maturing dendritic cells, suggesting a possible role in developmentally-controlled cell adhesion.

Also known as:

CYTIP; B31; CASP; Cbp HE; CYBR; CYTHIP; Cytip; CYTIP_HUMAN; Cytohesin binder and regulator; Cytohesin-associated scaffolding protein; Cytohesin-binding protein HE; Cytohesin-interacting protein;胞粘蛋白结合调节蛋白抗体 HE antibody Pleckstrin Homology Sec7 and Coiled-Coil Domains Binding Protein; Pleckstrin homology Sec7 and coiled-coil domains-binding protein.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, .

●

Immunogen: KLH conjugated synthetic peptide derived from human PSCDBP.

●

胞粘蛋白结合调节蛋白抗体Predicted Molecular Weight: 40kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl780Hu01乳铁传递蛋白(LTF)多克隆抗体Polyclonal Antibody to Lactoferrin (LTF)

kl780Mu01乳铁传递蛋白(LTF)多克隆抗体Polyclonal Antibody to Lactoferrin (LTF)

kl780Ra01乳铁传递蛋白(LTF)多克隆抗体Polyclonal Antibody to Lactoferrin (LTF)

kl667Hu01葡萄糖激酶(GCK)多克隆抗体Polyclonal Antibody to Glucokinase (GCK)

kl667Mu01葡萄糖激酶(GCK)多克隆抗体Polyclonal Antibody to Glucokinase (GCK)

kl667Ra01葡萄糖激酶(GCK)多克隆抗体Polyclonal Antibody to Glucokinase (GCK)

kl120Hu01精氨酸酶(ARG)多克隆抗体Polyclonal Antibody to Arginase (ARG)

kl120Mu01精氨酸酶(ARG)多克隆抗体Polyclonal Antibody to Arginase (ARG)

kl120Ra01精氨酸酶(ARG)多克隆抗体Polyclonal Antibody to Arginase (ARG)

kl846Hu01催乳素(PRL)多克隆抗体Polyclonal Antibody to Prolactin (PRL)

kl846Mu01催乳素(PRL)多克隆抗体Polyclonal Antibody to Prolactin (PRL)

kl846Ra01催乳素(PRL)多克隆抗体Polyclonal Antibody to Prolactin (PRL)

kl869Hu01丝裂原激活蛋白激酶10(MAPK10)多克隆抗体Polyclonal Antibody to Mitogen Activated Protein Kinase 10 (MAPK10)

kl869Mu01丝裂原激活蛋白激酶10(MAPK10)多克隆抗体Polyclonal Antibody to Mitogen Activated Protein Kinase 10 (MAPK10)

kl869Ra01丝裂原激活蛋白激酶10(MAPK10)多克隆抗体Polyclonal Antibody to Mitogen Activated Protein Kinase 10 (MAPK10)

kl986Hu01血红素结合蛋白(HPX)多克隆抗体Polyclonal Antibody to Hemopexin (HPX)

kl986Mu01血红素结合蛋白(HPX)多克隆抗体Polyclonal Antibody to Hemopexin (HPX)

kl986Ra01血红素结合蛋白(HPX)多克隆抗体Polyclonal Antibody to Hemopexin (HPX)

kl833Hu01血管性血友病因子(vWF)多克隆抗体Polyclonal Antibody to Von Willebrand Factor (vWF)

kl833Mu01血管性血友病因子(vWF)多克隆抗体Polyclonal Antibody to Von Willebrand Factor (vWF)

kl833Ra01血管性血友病因子(vWF)多克隆抗体Polyclonal Antibody to Von Willebrand Factor (vWF)

kl603Hu01载脂蛋白B100(APOB100)多克隆抗体Polyclonal Antibody to Apolipoprotein B100 (APOB100)

kl603Ra01载脂蛋白B100(APOB100)多克隆抗体Polyclonal Antibody to Apolipoprotein B100 (APOB100)