Quantity size:

0.2ml

Concentration:

1mg/ml  周期素D相关蛋白抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'周期素D相关蛋白抗体-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Several transcript variants encoding multiple isoforms have been found for this gene.

Also known as:

周期素D相关蛋白抗体Acute myelogenous leukemia 1 translocation 1 cyclin D related; Acute myelogenous leukemia 1 translocation 1 protein; AML1T1; CBFA2T1; CDR; Core binding factor runt domain alpha subunit 2 translocated to 1; Core binding factor runt domain alpha subunit 2 translocated to 1 cyclin D related; Cyclin D related; Cyclin D related protein; Eight twenty one protein; Eigth twenty one protein; ETO; ETO protein; MTG 8; MTG 8b; MTG8. MTG8 protein; MTG8b antibody Myeloid translocation gene on 8q22; Protein CBFA2T1; Protein ETO; Protein MTG 8; Protein MTG8; Runt related transcription factor周期素D相关蛋白抗体 1 translocated to 1 (cyclin D related); Runt related transcription factor 1 translocated to 1; Runt related transcription factor 1 translocated to 1 cyclin D related; Zinc finger MYND domain containing protein 2; ZMYND 2; ZMYND2.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human RUNX1T1/ETO.

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周期素D相关蛋白抗体Predicted Molecular Weight: 66kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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