细胞因子诱导凋亡抑制因子1抗体

英文名称    CIAPIN1    

中文名称    细胞因子诱导凋亡抑制因子1    

别    名    Anamorsin; CIAPIN 1; Cytokine induced apoptosis inhibitor 1; DRE2; CPIN1_HUMAN.      

研究领域    肿瘤  细胞生物  免疫学  细胞凋亡      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig, Cow,     

产品应用    WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    34kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CIAPIN1:51-150/312     

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

PubMed    PubMed    

产品介绍    CIAPIN1 (Cytokine induced apoptosis inhibitor 1) expression is dependent on growth factor stimulation. Overexpression confers resistance to apoptosis caused by IL3 deprivation. It may be required during hematopoiesis to mediate antiapoptotic effects of various cytokines. It also confers multidrug resistance in gastric cancer cells by upregulating the expression of MDR1 and MRP1.