波形蛋白单克隆抗体

英文名称    Vimentin    

中文名称    波形蛋白单克隆抗体    

别    名    FLJ36605; OTTHUMP00000019224; VIM; VIME_HUMAN; Vimentin.      

研究领域    肿瘤  细胞生物  发育生物学  信号转导  干细胞      

抗体来源    Mouse    

克隆类型    Monoclonal    

克 隆 号    3B7    

交叉反应    Human, Mouse, Rat,     

产品应用    WB=1:500-1000  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    53kDa    

细胞定位    细胞浆 细胞外基质     

性    状    Lyophilized or Liquid    

浓    度    1mg/ml    

免 疫 原    Recombinant human Vimentin Protein:     

亚    型    IgG    

纯化方法    affinity purified by Protein G    

储 存 液    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

PubMed    PubMed    

产品介绍    This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009]    

Vimentin—波形蛋白。是五种主要的中间丝之一，存在于各种正常和病理性间质来源的组织，如纤维母细胞、内皮细胞、淋巴细胞等正常细胞和肉瘤、淋巴瘤、黑色素瘤等肿瘤。波形蛋白是负责维持细胞骨架完整性的蛋白之一。