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抑制剂描述： 产品名称：Imipenem 产品别名：见爱必信官网 英文别名：Imipenem 靶点：Antibacterial CAS：74431-23-5 纯度：98% 外观：见爱必信官网 保存方法：store at -20℃ for one year（Powder）； in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months. 描述：Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor. 溶解性：Soluble in water 体外研究： Imipenem, a β-lactam antibiotic, binds to penicillin binding protein 2 with the highest affinity and produces rounded cells. The binding of imipenem causes cells to lyse quickly and thereby to release less free endotoxin. 体内研究：Imipenem has a very short half-life. Imipenem has antimycobacterial activity both in a mouse model and in humans at high risk for failure of treatment for MDR (multiple-drug-resistant) tuberculosis.
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