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抑制剂描述: 产品名称:Squalamine lactate 产品别名:见爱必信官网 英文别名:Squalamine lactate 靶点:Bacterial CAS:320725-47-1 纯度: 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder) 描述:Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity, and used for the treatment of neovascular age-related macular degeneration. 溶解性: 体外研究: Squalamine lactate has a more generalized effect on the cellular signaling cascade that is common to both VEGF and other growth factors. Squalamine blocks the action of VEGF and integrin expression, thereby inhibiting angiogenesis, when bound to calmodulin. 体内研究:Squalamine lactate has a more generalized effect on the cellular signaling cascade that is common to both VEGF and other growth factors. Squalamine blocks the action of VEGF and integrin expression, thereby inhibiting angiogenesis, when bound to calmodulin.
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