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抑制剂描述: 产品名称:Penicillamine 产品别名:见爱必信官网 英文别名:Penicillamine 靶点:Others CAS:52-67-5 纯度:>98% 外观:见爱必信官网 保存方法:-20°C 描述: Penicillamine (Cuprimine, Depen) is used as an antirheumatic and as a chelating agent in Wilson’s disease and is a chelating agent recommended for the removal of excess copper in patients with Wilson’s disease. From in vitro studies which indicate that one atom of copper combines with two molecules of penicillamine. Penicillamine also reduces excess cystine excretion in cystinuria. The mechanism of action of penicillamine in rheumatoid arthritis is unknown although it appears to suppress disease activity. Unlike cytotoxic immunosuppressants, penicillamine markedly lowers IgM rheumatoid factor but produces no significant depression in absolute levels of serum immunoglobulins. Also unlike cytotoxic immunosuppressants which act on both, penicillamine in vitro depresses T-cell activity but not B-cell activity. 溶解性:Water :28 mg/mL (187.7 mM) 体外研究: 体内研究:
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