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抑制剂描述: 产品名称:SU11652 产品别名:见爱必信官网 英文别名:SU11652 靶点:PDGFR CAS:326914-10-7 纯度:>97% 外观:见爱必信官网 保存方法:Store at -20° C 描述: SU11652 is a potent cell-permeable pyrrole-indolinone compound that acts as an ATP-competitive tyrosine kinase receptor and angiogenic inhibitor that exhibits greater selectivity for PDGFR-β (PDGFRβ, IC50 = 3 nM), Flk-1 (VEGFR2, IC50 = 27 nM), FGFR1 (IC50= 170 nM), and Kit family members (IC50=~10-500 nM) over EGFR (IC50 >20 μM). SU11652 displays anti-proliferative and pro-apoptotic properties in tumor cells. 溶解性:Soluble in DMSO (>25 mg/ml). 体外研究: 体内研究:
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