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抑制剂描述： 产品名称：PE859 产品别名：见爱必信官网 英文别名：PE859 靶点：Amyloid-β CAS：1402727-29-0 纯度：98% 外观：见爱必信官网 保存方法：store at -20℃ for one year（Powder） 描述： PE859 is a potent inhibitor of both tau and Aβ aggregation with IC50 values of 0.66 and 1.2 μM, respectively. 溶解性：DMSO : 50 mg/mL (111.48 mM; Need ultrasonic) 体外研究： PE859 inhibits the heparin-induced aggregation of both 3RMBD and full length tau in a concentration-dependent manner. In each assay, the IC50 values calculated at the last measurement periods are 0.81 μM, and 2.23 μM, respectively. PE859 inhibits tau aggregation through formation of beta-sheet structure. 体内研究：PE859 inhibits the heparin-induced aggregation of both 3RMBD and full length tau in a concentration-dependent manner. In each assay, the IC50 values calculated at the last measurement periods are 0.81 μM, and 2.23 μM, respectively. PE859 inhibits tau aggregation through formation of beta-sheet structure.
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