产品详情
兔抗DAGLA多克隆抗体
中文名称:兔抗DAGLA多克隆抗体
英文名称: Anti-DAGLA rabbit polyclonal antibody
别 名: diacylglycerol lipase alpha NSDDR; C11orf11; DAGLALPHA; DAGL(ALPHA)
相关类别: 一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
抗 原: DAGLA
反应种属: Human, Mouse, Rat
标记物: Unconjugate
克隆类型: rabbit polyclonal
Background: | Members of the AB hydrolase superfamily have diverse catalytic functions and play a crucial role in the metabolism of lipids. DAGLα (diacylglycerol lipase alpha), also known as NSDDR or C11orf11, is a 1,042 amino acid multi-pass membrane protein that belongs to the AB hydrolase superfamily. Highly expressed in brain and pancreas, DAGLα uses calcium as a cofactor to catalyze the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), a reaction that is required for axonal growth and for retrograde synaptic signaling at mature synapses. DAGLα functions as at optimal pH of 7 and its activity is inhibited by p-hydroxy-mercuri-benzoate and HgCl2. The gene encoding DAGLα maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. |
Applications: | ELISA, IHC |
Name of antibody: | DAGLA |
Immunogen: | Synthetic peptide of human DAGLA |
Full name: | diacylglycerol lipase alpha |
Synonyms: | NSDDR; C11orf11; DAGLALPHA; DAGL(ALPHA) |
SwissProt: | Q9Y4D2 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human liver cancer and Human esophagus cancer |
IHC Recommend dilution: | 25-100 |