产品详情
生物素标记兔抗人IgM
中文名称: 生物素标记兔抗人IgM
英文名称:Biotin-conjugated Rabbit anti-human IgM
相关类别:Biotin标记二抗
储存:冷冻 (-20℃)
Background | IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to its large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to its high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. |
Applications | Optimal tested applications and working dilutions must be determined by the end user. |
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