产品详情
兔抗TBX1多克隆抗体
中文名称: 兔抗TBX1多克隆抗体
英文名称: Anti-TBX1 rabbit polyclonal antibody
级 别: DGS; TGA; VCF; CAFS; CTHM; DGCR; DORV; VCFS; TBX1C; CATCH22
抗 原: TBX1
储 存: 冷冻(-20℃)
宿 主: Rabbit
相关类别: 一抗
反应种属: Human
标记物: Unconjugate
克隆类型: rabbit polyclonal
技术规格:兔抗TBX1多克隆抗体
Background: | This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Applications: | ELISA, WB, IHC |
Name of antibody: | TBX1 |
Immunogen: | Synthetic peptide of human TBX1 |
Full name: | T-box 1 |
Synonyms: | DGS; TGA; VCF; CAFS; CTHM; DGCR; DORV; VCFS; TBX1C; CATCH22 |
SwissProt: | O43435 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human liver cancer |
IHC Recommend dilution: | 25-100 |
WB Predicted band size: | 43 kDa |
WB Positive control: | 293T and Hela cell lysates |
WB Recommended dilution: | 500-2000 |