产品详情
小鼠抗GCLC单克隆抗体
中文名称: 小鼠抗GCLC单克隆抗体
英文名称: Anti-GCLC mouse monoclonal antibody
别 名: GCL; GCS; GLCL; GLCLC
抗 原: GCLC
储 存: 冷冻(-20℃) 避光
宿 主: Mouse
反应种属: Human , Rat , Monkey
相关类别: 一抗
标 记 物: Unconjugate
克隆类型: mouse monoclonal
Background: | Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct |
Applications: | WB, IHC |
Name of antibody: | GCLC |
Immunogen: | Fusion protein of human GCLC |
Full name: | glutamate-cysteine ligase, catalytic subunit (GCLC), transcript variant 1 |
Synonyms: | GCL; GCS; GLCL; GLCLC |
SwissProt: | P48506 |
IHC positive control: | human pancreas tissue and carcinoma of human thyroid tissue |
IHC Recommend dilution: | 30-150 |
WB Predicted band size: | 73 kDa |
WB Positive control: | HepG2, A549, COS7, Jurkat, PC12, MCF-7 cell lysates |
WB Recommended dilution: | 200-1000 |
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