WB Positive control:

LNCAP cell, Mouse heart tissue, HUVEC cell lysates

WB Predicted band size:

67 kDa

IHC Recommend dilution:

50-200

IHC positive control:

Human cervical cancer

ELISA Recommended dilution:

5000-10000

SwissProt:

P27824

Synonyms:

CNX; P90; IP90

Full name:

calnexin

Immunogen:

Synthetic peptide of human CANX

Name of antibody:

CANX

Applications:

ELISA, WB, IHC

Background:

This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding different isoforms have been described.