别称

KIAA1794

 宿主

Rabbit

 适应种属

Human

 亚型

IgG

 验证应用

ELISA, WB, IF, IP

产品信息

产品名称

anti- FANCI antibody

货号

QSab03009

规格

100μg

状态

liquid

纯化方法

Immunogen affinity purified

纯度

≥95% as determined by SDS-PAGE

宿主

Rabbit

克隆性

polyclonal

亚型

IgG

存储

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

背景介绍

Plays an essential role in the repair of DNA double-strand breaks by homologous recombination and in the repair of interstrand DNA cross-links(ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA: binds both single-stranded DNA(ssDNA) and double-stranded DNA(dsDNA). Participates in S phase and G2 phase checkpoint activation upon DNA damage.

免疫原信息

免疫原

Fanconi anemia, complementation group I

别称

KIAA1794

分子量

150 kDa

应用

验证应用

ELISA, WB, IF, IP

建议稀释比例

WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200