产品详情
别称
KIAA1794
宿主
Rabbit
适应种属
Human
亚型
IgG
验证应用
ELISA, WB, IF, IP
产品信息
产品名称
anti- FANCI antibody
货号
QSab03009
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
宿主
Rabbit
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
背景介绍
Plays an essential role in the repair of DNA double-strand breaks by homologous recombination and in the repair of interstrand DNA cross-links(ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA: binds both single-stranded DNA(ssDNA) and double-stranded DNA(dsDNA). Participates in S phase and G2 phase checkpoint activation upon DNA damage.
免疫原信息
免疫原
Fanconi anemia, complementation group I
别称
KIAA1794
分子量
150 kDa
应用
验证应用
ELISA, WB, IF, IP
建议稀释比例
WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200