别称

IDS, iduronate 2 sulfatase, Idursulfase

 宿主

Mouse

 适应种属

Human

 亚型

IgG1

 验证应用

ELISA, WB, IHC, IF

产品信息

产品名称

anti- Iduronate 2 sulfatase antibody

货号

QSab04130

规格

100μg

状态

liquid

纯化方法

Protein A+G purification

纯度

≥95% as determined by SDS-PAGE

宿主

Mouse

克隆性

monoclonal

亚型

IgG1

存储

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

背景介绍

Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. IDS is synthesized as two precursor forms of 76 and 90 kDa that are converted, through a 62 kDa intermediate, to 55 and 45 kDa mature polypeptides due to an internal proteolytic cleavage (PMID: 10838181).

免疫原信息

免疫原

iduronate 2-sulfatase

别称

IDS, iduronate 2 sulfatase, Idursulfase

分子量

76 kDa, 55 kDa

应用

验证应用

ELISA, WB, IHC, IF

建议稀释比例

WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200