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 Streptomyces tacrolimicus 拉丁名

ATCC 55098 编号

Deposited As Streptomyces sp.

Strain Designations 菌种别名 MA 6858 [CIBE 9021-401]

Application 

Produces tacrolimus FK-506, FK506

Production of the immunosuppressant FK-506

Isolation 分离基物 White-tailed deer dung, Montgomery Co., VA

Biosafety Level 安全等级 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format freeze-dried

Disclosure This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC.

Preceptrol no

Type Strain 模式菌株 no

Medium 培养基 ATCC Medium 196: Yeast malt extract agar

Growth Conditions 生长条件

Temperature 培养温度 : 26.0°C

Name of Depositor 寄存人 Merck & Co., Inc.

U.S. Patent Number 

5,116,756

Disclosure This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC.

Isolation 

White-tailed deer dung, Montgomery Co., VA

References 参考文献 

Dumont F, et al. Process for producing FK-506. US Patent 5,116,756 dated May 26 1992

Martinez-Castro M, et al. Streptomyces tacrolimicus sp. nov. a Low Producer of the Immunosuppressant FK506. Int. J. Syst. Evol. Microbiol. 2010 June 4. PubMed 20525816.